Very Efficient Way to Extract DNA from a PCR

UC Davis
Microbiology and Immunology
Graduate Student

Overall

Quality of Results

Ease-of-Optimization

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Company:

Qiagen

Product Name:

QIAquick PCR Purification Kit (250)

Catalog Number:

28106

A plasmid was linearized and target genes were amplified by PCR. For the next step (Gibson Assembly) these fragments were purified through the Kit.

Experimental Design and Results Summary

Application

To purify the PCR reaction.

Starting Material

PCR product

Tips

Before applying this kit, you should run a gel to check if there are any additional bands besides your desired product.

Results Summary

The extracted DNA content is much higher than doing a gel extraction. Here you only need to start a one PCR tube for one reaction. If using the gel you would need to start 8 to reach enough DNA content.

DOI or PMID #

N/A

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Summary

The Good

You dont loose a lot of your product.

The Bad

None

The Bottom Line

This is a very efficient and fast way to extract the generated DNA form your PCR reaction.

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