Review For Dead Cell Removal Kit

Northwestern University
Cell and Molecular Biology
Research Associate

Overall

Quality of Results

Ease-of-Optimization

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Company:

Miltenyi Biotec

Product Name:

Dead Cell Removal Kit

Catalog Number:

130-090-101

The overall goal of my research is to understand sexual transmission of HIV. The specific goal of this project was to phenotype the cells infected at various mucosal sites. This product was chosen due to coworker recommendation.

Experimental Design and Results Summary

Application

Flow cytometry analysis

Starting Material

Rhesus Macaque tissues and isolated PBMCs

Protocol Overview

Cells were isolated from tissue or from blood. After enzymatic and mechanical cell isolation from tissue dead cell removal kit was used according to manufacturer's recommendation. Cells were then stained with Live dead stain to test the yield of live cells.

Tips

Filter cells a bit at a time to prevent filter clogging.

Results Summary

This kit did not work as ideal as expected.

DOI or PMID #

N/A

Additional Notes

On the image included live cells are represented on x axis while SSC-A is shown on y axis

Image Gallery

Summary

The Good

More live cells seen than when no kit was used

The Bad

Not completely successful in separating the cell debris

The Bottom Line

This kit is useful to eliminate some of the dead cells and debris however not perfect.

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