Isotope Control for RBC Surface Associated IgG Test

Veterinary Diagnostic Laboratory
Kansas State University
RA

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Company:

Jackson ImmunoResearch Laboratories, Inc.

Product Name:

Rabbit IgG FITC

Catalog Number:

313-096-003

The aim of this experiment was to determine the proportion of RBC'S bound to different immunoglobulins from dogs that have immune mediated hemolytic anemia. This antibody was used as an isotope control for the Rabbit anti dog IgG antibody which is used to detect bound RBC to IgG.

Experimental Design and Results Summary

Applications

Flow Cytometry

Sample

Whole blood in EDTA

Primary Incubation

100ul of 1:100diluted 1mg/ml antibody with the 100ul of washed cells incubated for 30mins in dark.

Blocking Agent

NA

Secondary Incubation

NA

Tertiary Incubation

NA

Detection

FACS CAlibur

Results Summary

The results for this particular antibody helps us to determine the negative population of cells that did not stain. Hence it serves as a good isotype control.

Additional Notes

None

Image Gallery

Summary

The Good

Works well as an Isotype

The Bad

None

The Bottom Line

Good control.

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