Bench Tips

Advice on how to solve a challenging lab task or technique provided by a subject matter expert.

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Tackling Problems with HPLC Purification of Oligonucleotides
July 21, 2017
Tips on improving efficiency by increasing yields and shortening purification times. read more
Overcoming a Common Pipetting Challenge
July 19, 2017
Learn how positive displacement can resolve ubiquitous problems. read more
Tips to Evaluate qPCR Master Mixes
July 10, 2017
Careful experimental design and analysis is required to investigate reagent performance when choosing among master mixes. read more
Multiplex Immunoassays: Five Tips for Sample Preparation
June 28, 2017
Simultaneous detection of multiple analytes in a single well or reaction is just one of the benefits of bead-based multiplexed assays. read more
Sample Quantity and Quality Control for Next-Gen Sequencing
June 27, 2017
Robust procedures for sample input are essential to ensure consistent results through the workflow. read more
Enhancing Bacterial Research Using Flow Cytometry
June 23, 2017
Find out how to prevent many of the pitfalls that occur in microbial analysis on the flow cytometer. read more
Production and Isolation of Exosomes from Conditioned Tissue Culture Media
March 09, 2017
Exosomes participate in a variety of cellular activities and have been shown to be isolatable from multiple body fluids, including saliva, urine, ... read more
How to Select and Use Plastics Successfully in the Lab
December 06, 2016
Working in a lab presents a number of health and safety challenges, especially when working with chemicals and solutions. On one hand, to cope with ... read more
Multiplex Immunoassays: Five Tips for Optimizing Your Experiments
November 29, 2016
Biomedical and pharmaceutical research increasingly requires concurrent measurement of multiple biomarkers to reveal early indications of disease or ... read more
Choosing a Plastic Labware Brand
November 21, 2016
Experimental results are only as good as a lab’s scientists and the tools they use. Those tools often include plastic labware—bottles, carboys, ... read more
Purification of Recombinant F(Ab')2 Fragments and Their Various Applications
November 08, 2016
Fragment antigen binding domains, or F(ab) fragments, are derived from the upper branches of the ‘Y’-shaped antibody molecule. They form the antigen ... read more
Digital PCR: Helpful Tips When Using Droplet Partitioning Technology
November 07, 2016
The concept of digital PCR (dPCR) for nucleic acid detection and quantification is not new. In 1992, Sykes et al. described a method in which they ... read more
Fluorescent Peptides: Valuable Tools for Medical Research
October 25, 2016
To gain a better understanding of disease states, researchers utilize model cell systems to conduct their studies. While cell systems provide ... read more
Tips on Downstream Purification Processes
October 17, 2016
Once protein purification work surpasses a certain scale in terms of volume, a measured and step-wise development of the bioseparation process is ... read more
Overcoming Purification Hurdles with Mixed-Mode Chromatography
September 12, 2016
Bacteria and viruses are nature’s shapeshifters, able to alter the make-up of their surface proteins in order to evade recognition by host immune ... read more
Tips for Preparing Process-Scale Chromatography Columns
September 12, 2016
Column chromatography has been used for many years to successfully characterize, purify and manufacture products for the food and drug industries. ... read more
Useful Tips for Fab Protein Purification
July 08, 2016
While protein purification is a well-established, conventional and highly trusted discipline, the approaches it employs can be as diverse as its ... read more
Lab Scale Protein Purification
June 13, 2016
Protein purification at the lab scale bridges the gap between small-scale exploratory protein purification and high-throughput operations, such as ... read more
Non-invasive small animal imaging using smart activity based probes (iABP™).
May 11, 2016
Small animal imaging enables researchers to examine below the surface and understand cellular processes in a relevant biological environment. While in... read more
Advantages of Multidimensional (Multi-D) Chromatography-what’s it all about
April 11, 2016
Many laboratories today are faced with producing timely and accurate results at reduced cost. The pace of life science R&D and manufacturing is being... read more