NGS Assays

Next-generation sequencing (NGS) assays are tools for genome-wide, targeted expression analysis, offering high-throughput capabilities to support molecular diagnostics and research. These assays follow an approach similar to multiplexed RT-PCR, simultaneously amplifying multiple RNA target sequences with the depth and precision supported by NGS platforms. They enable diverse applications including tumor mutational burden assessment, microsatellite instability detection, homologous recombination deficiency analysis, antibody isotype profiling, somatic hypermutation quantification, and clonality evaluation. Kits are generally flexible and can accommodate diverse sample types ranging from total RNA and FFPE or fresh frozen tissue to bone marrow, whole blood, PBMCs, and sorted cells. Visit the supplier page for more information, including validated applications and supported NGS platforms.