Human Caspase-1/ICE Quantikine ELISA Kit DCA100 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemHuman Caspase-1/ICE Quantikine ELISA Kit
CompanyR&D Systems, a Bio-Techne Brand
Price $680.00Supplier Page View Company Product Page
Catalog NumberDCA100
Quantity1 Kit
ApplicationsELISA
Detection Range6.25 - 400 pg/mL
ReactivityHuman
Sample TypeCell Culture Supernates (100 uL)
Sensitivity1.24 pg/mL
Detection TargetCaspase-1
Assay Time3 hours
StorageStore the unopened product at 2 - 8 °C. Do not use past expiration date
NCBI Full Gene Namecaspase 1
NCBI Gene AliasesICE, IL1BC, P45

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Liver Sinusoidal Endothelial Cells Promote Metabolic Dysfunction-associated Steatohepatitis Progression via Interleukin-1R1-mediated Chemokine Production Induced by Macrophage-derived Interleukin-1βCellular and Molecular Gastroenterology and HepatologyJanuary 1, 2026Kenji Fukumoto, Hayato Hikita, Yoshinobu Saito, Yuki Makino, Kazumasa Soma, Seiya Kato, Yoichi Sasaki, Yuta Myojin, Katsuhiko Sato, Sadatsugu Sakane, et al.enzyme-linked immunosorbent assay (ELISA) (DY201-05; R&D Systems) and a Human caspase-1/ICE Quantikine ELISA Kit (DCA100; R&D Systems), respectively. Western Blotting The protocols for sample preparation, electrophoresis,

(2) Targeting Caspase-1 in osteoarthritis: multi-omics insights into the effects of VX-765 on human chondrocyte function and phenotypeFront ImmunolOctober 3, 2025Jian Mei, Nicole Schäfer, Penghui Wei, Zhiheng Kong, Shushan Li, Patrick Pann, Marianne Ehrnsperger, Brian Johnstone, Eva Matalova, Susanne Grässelcommercially available ELISA kits: the Quantikine™ Human Caspase-1/ICE Immunoassay (R&D Systems, Cat. No. DCA100) and the RayBio® Human Caspase-1 ELISA Kit (RayBiotech, Cat. No. ELH-Caspase1), following the manufacturers’

(3) Multimodal profiling of proinflammatory protease activity identifies caspase-1 as a target for lung cancer interceptionbioRxiv : the preprint server for biologyJuly 2, 2025Wang CS, Zhong Q, Wang ST, Martin-Alonso C, Neaher S, Patel S, Parisi T, Kirkpatrick JD, Sequist LV, Jacks TE, et al.

(4) Dopamine-driven increase in IL-1β in myeloid cells is mediated by differential dopamine receptor expression and exacerbated by HIVJournal of neuroinflammationMarch 23, 2025Matt SM, Nolan R, Manikandan S, Agarwal Y, Channer B, Oteju O, Daniali M, Canagarajah JA, LuPone T, Mompho K, et al.

(5) A Mixture of Water-Soluble Polysaccharides Reduces Caspase-1 and IL-1β Inflammatory Responses by Cutibacterium acnes in vitro in Reconstructed Human Epidermis (RHE)Clinical, Cosmetic and Investigational DermatologyNovember 21, 2024James V Gruber, Nicole Terpak, Sebastien Massard, Xiang Chen, Yurah Kimavailable kit and according to internal procedures. • Human Caspase-1/ICE Immunoassay (Catalog Number DCA100, R&D Systems, Minneapolis, MN) • Human IL-1β (Catalog Number DLB50, R&D Systems, Minneapolis, MN) Optical

(6) C4b-Binding Protein and Factor H Attenuate NLRP3 Inflammasome-Mediated Signalling Response during Group A Streptococci Infection in Human CellsJournal of Innate ImmunityNovember 4, 2024Serena Bettoni, Mateusz Dziedzic, Damien Bierschenk, Maja Chrobak, Michal Magda, Maisem Laabei, Ben C. King, Kristian Riesbeck, Anna M. BlomCaspase-1 p20 fragments were measured using the Human Caspase-1/ICE Quantikine ELISA Kit (R&D systems DCA100). Mature IL-1β was detected using IL-1β specific HEK-Blue reporter cells (Invivogen). Briefly, 50 μL

(7) The Association between IL-1β and IL-18 Levels, Gut Barrier Disruption, and Monocyte Activation during Chronic Simian Immunodeficiency Virus Infection and Long-Term Suppressive Antiretroviral TherapyInternational journal of molecular sciencesAugust 9, 2024Thirugnanam S, Wang C, Zheng C, Grasperge BF, Datta PK, Rappaport J, Qin X, Rout N.were quantitatively determined using the Quantikine™ ELISA Human caspase-1/ICE Immunoassay (Catalog# DCA100, R&D Systems, Minneapolis, MN, USA). The assay was conducted according to the manufacturer’s instructions.

(8) Vaginal microbes alter epithelial transcriptome and induce epigenomic modifications providing insight into mechanisms for susceptibility to adverse reproductive outcomesResearch squareMay 31, 2024Elovitz M, Anton L, Cristancho A, Ferguson B, Joseph A, Ravel J.

(9) Tracking the therapeutic efficacy of a ketone mono ester and β-hydroxybutyrate for ulcerative colitis in rats: New perspectivesToxicology and applied pharmacologyMay 1, 2024Mohammed OA, Saber S, Abdel-Reheim MA, Alamri MMS, Alfaifi J, Adam MIE, Alharthi MH, Eleragi AMS, Eltahir HB, Abdalla MO, et al.

(10) Increased serum caspase-1 in adult-onset Still's diseasePloS oneJanuary 1, 2024Matsumoto H, Yoshida S, Koga T, Fujita Y, Sumichika Y, Saito K, Temmoku J, Asano T, Sato S, Mizokami M, et al.

(11) Vaginal microbes alter epithelial transcriptomic and epigenomic modifications providing insight into the molecular mechanisms for susceptibility to adverse reproductive outcomesResearch squareNovember 16, 2023Elovitz M, Anton L, Cristancho A, Ferguson B, Joseph A, Ravel J.

(12) Lunasin reduces the susceptibility of IL-10 deficient mice to inflammatory bowel disease and modulates the activation of the NLRP3 inflammasomeThe Journal of nutritional biochemistrySeptember 1, 2023Nieto-Veloza A, Hong S, Reeder M, Sula MJ, D'Souza DH, Zhong Q, Dia VP.

(13) Coronary Artery Plaque Composition and Severity Relate to the Inflammasome in People With Treated Human Immunodeficiency VirusOpen forum infectious diseasesMarch 1, 2023Schnittman SR, Kitch DW, Swartz TH, Burdo TH, Fitch KV, McCallum S, Flynn JM, Fulda ES, Diggs MR, Stapleton JT, et al.(K151ADSS-1). Interleukin-18 and caspase-1 were measured using Quantikine ELISAs by R&D Systems (DL180 and DCA100, respectively). All samples were run in duplicate with intraindividual variability <25%. Statistical

(14) Exogenous melatonin alleviates neuropathic pain-induced affective disorders by suppressing NF-κB/ NLRP3 pathway and apoptosisScientific reportsFebruary 6, 2023Mokhtari T, Yue LP, Hu L.

(15) Ubiquitination as a key regulatory mechanism for O(3)-induced cutaneous redox inflammasome activationRedox biologyOctober 1, 2022Ferrara F, Cordone V, Pecorelli A, Benedusi M, Pambianchi E, Guiotto A, Vallese A, Cervellati F, Valacchi G.indicated timepoints, and Caspase 1 levels were measured by Human Caspase 1/ICE Quantikine ELISA Kit (cat. DCA100, R&D System, Inc., Minneapolis, MN, USA), according to the manufacture’s protocol. IL-1β levels were

(16) Modulation of MAPK- and PI3/AKT-Dependent Autophagy Signaling by Stavudine (D4T) in PBMC of Alzheimer's Disease PatientsCellsJuly 12, 2022La Rosa F, Zoia CP, Bazzini C, Bolognini A, Saresella M, Conti E, Ferrarese C, Piancone F, Marventano I, Galimberti D, et al.

(17) The Placental NLRP3 Inflammasome and Its Downstream Targets, Caspase-1 and Interleukin-6, Are Increased in Human Fetal Growth Restriction: Implications for Aberrant Inflammation-Induced Trophoblast DysfunctionCellsApril 21, 2022Alfian I, Chakraborty A, Yong HEJ, Saini S, Lau RWK, Kalionis B, Dimitriadis E, Alfaidy N, Ricardo SD, Samuel CS, et al.

(18) Lipopolysaccharide stimulation test on cultured PBMCs assists the discrimination of cryopyrin-associated periodic syndrome from systemic juvenile idiopathic arthritisScientific reportsJune 7, 2021Wu CY, Fan WL, Chiu YM, Yang HY, Lee WI, Huang JL.sandwich enzyme-linked immunosorbent assay reagent kits (DY201-05, DY206-05, DY318-05, DY210-05 and DCA100, respectively) obtained from R&D system (Minneapolis, MN, USA). Serum amyloid A (SAA) was measured by

(19) Hydroquinone Induces NLRP3-Independent IL-18 Release from ARPE-19 CellsCellsJune 6, 2021Bhattarai N, Korhonen E, Mysore Y, Kaarniranta K, Kauppinen A.

(20) Chalcones Display Anti-NLRP3 Inflammasome Activity in Macrophages through Inhibition of Both Priming and Activation Stepsâ€”Structure-Activity-Relationship and Mechanism StudiesMoleculesDecember 16, 2020Wohn-Jenn Leu, Jung-Chun Chu, Jui-Ling Hsu, Chi-Min Du, Yi-Huei Jiang, Lih-Ching Hsu, Wei-Jan Huang, Jih-Hwa Guhother chemical compounds were obtained from Sigma-Aldrich (St. Louis, MO, USA). Human Caspase-1/ICE (DCA100), IL-6 (D6050), and IL-1β/IL-1F2 (DLB50) Immunoassay Kits were from R&D system (Minneapolis, MN, USA).

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12/31/2020The Caspase-1 ELISA Works for Detection of Active Caspase-1 Anonymous ReviewI used this caspase-1 ELISA kit to measure the cleaved caspase-1 (p20) from culture supernatant of THP-1 cells incubated with or without LPS+ATP. The cleaved caspase-1 can be measured from culture ... Read Review

Caspase-1 ELISA

Human Caspase-1/ICE Quantikine ELISA Kit

Caspase-1 ELISA

Human Caspase-1/ICE Quantikine ELISA Kit from R&D Systems, a Bio-Techne Brand

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R&D Systems, a Bio-Techne Brand

Citations (54)

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Human Caspase-1/ICE Quantikine ELISA Kit from R&D Systems, a Bio-Techne Brand

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