Brilliant Violet 605™ anti-mouse CD4 100451 from BioLegend

Product Specs
ItemBrilliant Violet 605™ anti-mouse CD4
CompanyBioLegend
Price $309.00Supplier Page View Company Product Page
Catalog Number100451
Quantity50 µg
ApplicationsFC - Quality tested
Concentration0.2mg/ml
Conjugate/TagBrilliant Violet 605™
FormatPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
ReactivityMouse
IsotypeRat IgG2b, kappa
CloneGK1.5
HostRat
Antibody TypePrimary
ImmunogenMouse CTL clone V4
NCBI Full Gene NameCD4 antigen
NCBI Gene AliasesL3T4, Ly-4
ClonalityMonoclonal
TargetCD4

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BioLegend

8999 BioLegend Way

San Diego, California 92121

United States

Phone: 1-877-246-5343 Toll-Free, USA & Canada
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Fax: 1-877-455-9587

Company Profile

Website: biolegend.com

(1) Naive CD4+ T cells synthesize a hyaluronan-rich glycocalyx that is diminished following activationiScienceJuly 17, 2026Laxmi Prasad Adhikari, Jessica Contreras, Kristen M. Patterson, Meghan M. Moran, Erin N. Howe, Anna H.K. Plaas, Joseph M. ReynoldsRESOURCE,SOURCE,IDENTIFIER Antibodies,Antibodies,Antibodies ,, Brilliant Violet 605 anti-mouse CD4 (clone GK1.5),Biolegend,Cat# 100451; RRID: AB_2564591 Brilliant Violet 421 anti-mouse CD62L (clone MEL-14),Biolegend,Cat# 104435; RRID:

(2) Tobemstomig, a Novel Bispecific Antibody, Preferentially Blocks PD-1 and LAG-3 on CD8 TILs to Expand Stem-like T Cells for Sustained Tumor ControlCancer Res CommunJuly 1, 2026Patrick A.A. Weber, Mario Perro, Valeria G. Nicolini, Klas Hatje, Silvia Jenni, Stefanie Briner, Esther Bommer, Manuela Tanner, Sylvain Pilet, Tamara Hüsser, et al.[clone 53-6.7, 100748, BioLegend, RRID: AB_2562100 (1:100)], bin channel BV605 anti-CD4 [clone GK1.5, 100451, BioLegend, RRID: AB_2564591 (1:100)], and BV605 anti-CD11c [clone N418, 117333, BioLegend, RRID: AB_11204262

(3) Targeting Periodontitis with Treg-Derived Extracellular Vesicles: Modulation of Macrophages and CD8+ T-Cell ResponsesInternational Journal of Molecular SciencesJune 29, 2026Carolina Rojas, Luis González-Osuna, Michelle García, Alfredo Sierra-Cristancho, Luis Daniel Sansores-España, Paola Carvajal, Lesley A. Smyth, Karina Pino-Lagos, Rolando VernalAntibody,Clone,Fluorochrome,Code,Supplier anti-CD4,GK1.5,BV605 2,100451,Biolegend 6 anti-CD8α,53-6.7,BUV396 3,563786,BD Biosciences 7 anti-CD25,PC61,BV421,102034,Biolegend anti-CD45,30-F11,BV711,103147,Biolegend anti-IFN-γ,XMG1.2,APC

(4) Efficacy and immunogenic effects of Tumor Treating Fields ( TTFields ) in preclinical models of pancreatic ductal adenocarcinoma, with and without gemcitabine/nab‐paclitaxelInternational Journal of CancerJune 15, 2026Tal Kan, Tharwat Haj Khalil, Yiftah Barsheshet, Tali Voloshin, Lilach Koren, Bella Koltun, Cfir David, Kerem Wainer‐Katsir, Avital Vorontsova, Boris Brant, et al.CD45‐AF700 (103128, BioLegend), CD11b‐PerCP (101230, BioLegend), CD3e‐BV750 (100249, BioLegend), CD4‐BV605 (100451, BioLegend), CD8a‐PE‐Fire 700 (100792, BioLegend), Ly6G‐BV650 (127641, BioLegend), Ly6C‐BV570 (128029,

(5) SPIC-dependent erythrophagocytic macrophages drive granuloma formation and pathogen persistence during intracellular bacterial infectionbioRxivMay 30, 2026Aaron Fountain, Weixian Lin, Max J. Lain, Yuan Xue, Trung H. M. PhamBlue,BD Biosciences,Cat# 558214 CD4 APC,BioLegend,Cat# 100412 CD4 Brilliant Violet 605,BioLegend,Cat# 100451 CD8 Alexa Fluor 700,ThermoFisher (Invitrogen),Cat# 56-0081-82 CD11b Alexa Fluor 594,BioLegend,Cat#

(6) CGRP reception potentiates anxiety in an influenza A derived immune engrambioRxivMay 26, 2026Sarah K. Monroe, Benjamin A. Devlin, Ariana Vaida, Nikhita Nanduri, Hannah A. Staley, Estefany Y. Reyes, Dang M. Nguyen, Julia E. Dziabis, Aja Pragana, Seneca R. Oxendine, et al.Horizon,564279,1:200 PE-CY7,NK1.1,BioLegend,108714,1:200 PE,TCRB,Biolegend,109207,1:200 BV605,CD4,BioLegend,100451,1:200 BV785,CD8,Biolegend,100750,1:200 APC,CD19,BioLegend,115511,1:200 PE-Cy5,CD62L,BioLegend,104410,1:200 Flow cytometry

(7) Second-order regulation: IFN-γ suppresses IL-17A-mediated type 3 inflammationFront ImmunolMay 11, 2026Vijay Raaj Ravi, Sophia H. Maxfield, Emma N. Niszczak, Hannah Y. Kim, Olivia S. Harlow, Anjali Kakarla, Kalyn D. Whitehead, Anukul T. ShenoyCD8 (Clone 53-6.7, BD Biosciences, Cat# 612898), BV605 anti-mouse CD4 (Clone GK1.5, Biolegend, Cat# 100451), APC anti-mouse IL-17A (Clone TC11-18H10.1, Biolegend, Cat# 506916), APC-Cy7 anti-mouse IFN-γ (Clone

(8) Insufficient erythrocyte-derived S1P: A pathogenic driver and diagnostic biolipid for tumor progressioniScienceApril 17, 2026Zhenjiang Li, Weilun Huang, Zhouzhou Yao, Juncheng Wang, Wenhao Xiao, Qi Guo, Changhan Chen, Tingting Xie, Zhiyu Yang, Qingyang Liu, et al.AB_312981 Anti-mouse CD45 (BV711),BioLegend,Cat# 103147; RRID: AB_2564383 Anti-mouse CD4 (BV605),BioLegend,Cat# 100451; RRID: AB_2564591 Anti-mouse CD8a (FITC),BioLegend,Cat# 100706; RRID: AB_312745 Anti-mouse CD8a (APC),BioLegend,Cat#

(9) A MERTK-Targeting Antibody-Drug Conjugate Selectively Depletes M2 Tumor-Associated Macrophages and MERTK-Expressing Cancer CellsCancer ResApril 15, 2026Shugaku Takeda, Subhasree Sridhar, Daniel Schefer, Celia Andreu-Agullo, Pui C. Lo, Minhee Lee, Robert Busby, David M. Darst, Anne Assmus, Suresh Anaganti, et al.(Biolegend: CD45-BV785, 103149, RRID:AB_2564590; CD3-PerCp Cy5.5, 100217, RRID:AB_1595597; CD4-BV605, 100451, RRID:AB_2564591; CD8a-AF700, eBioscience, 56-0081-82, RRID:AB_494005). Following wash with PBS, the

(10) RPS19 and RPL5 haploinsufficient models reveal divergent ribosomal subunit controls of fetal hematopoiesisNature CommunicationsApril 8, 2026Yuefeng Tang, Te Ling, Rashid Mehmood, Alexis Bertrand, Julien Papoin, Mushran Khan, Riaz Rao, Jianing Xu, Vincent Schulz, James Palis, et al.hematologic malignancies in DBAS. Methods Antibodies The following antibodies were used: CD4-BV605 (Biolegend, #100451, 1:200); CD8a-BV6-5 (Biolegend, #100744, 1:200); Ter119-BV605 (Biolegend, #116239, 1:200); CD45R/B220-BV605

(11) Targeted inhibition of Nrf2 potentiates antitumor immunity and enhances the efficacy of immunotherapy in hepatocellular carcinomaJ Immunother CancerMarch 24, 2026Yan Zhu, Maoxuan Liu, Xiaokai Fan, Yingying Xu, Xueling Diao, Jiacheng Bi, Xiaochun Wan, Yehuda G Assaraf, Hang Fai Kwok, Liang ChenBioLegend: anti-mouse CD45 (#103137, #103138, #103154), anti-mouse CD3ε (#100306, #100216), anti-mouse CD4 (#100451), anti-mouse CD8α (#100722, #100792), anti-human/mouse Granzyme B (#372204, #396408, Isotype ctrl #400141),

(12) Identifying microbial protease allergens through protein language model-guided homologyCell SystemsMarch 18, 2026Kumar Thurimella, Elena Wu, Chenhao Li, Daniel B. Graham, Róisín M. Owens, Damian R. Plichta, Caroline L. Sokol, Ramnik J. Xavier, Sergio BacalladoClone: URA-1",Bioledgend,"Cat# 146808, RRID:AB_2563390" "Anti-mouse CD4, Clone: GK1.5",BioLegend,"Cat# 100451, RRID:AB_2564591" "Anti-mouse CD4, Clone: GK1.5",BioLegend,"Cat# 100412, RRID:AB_312697" "Anti-mouse

(13) Radiation-Enhanced CD24 Membrane Trafficking via GPI Anchoring Mediates Anti-Tumor Immune EvasionCancer ResearchMarch 16, 2026Lingyi Kong, Minqi Zhou, Wenqian Yuan, Yijun Wang, Xixi Liu, Jiacheng Wang, Weidong Zhong, Qinyan Chen, Pengfei Li, Tingting Pu, et al.#157213, RRID: AB_2894427), CD3 (BioLegend, cat. #100245, RRID: AB_2565882), CD4 (BioLegend, cat. #100451, RRID: AB_2564591), and CD8 (BioLegend, cat. #100751, RRID: AB_2561389). Subsequently, cells were fixed

(14) Facile induction of immune tolerance by an interleukin-2–TGFβ surrogate agonistNatureMarch 11, 2026Qinli Sun, Alison K. Barrett, Masato Ogishi, Huiyun Lyu, Hua Jiang, Honghui Liu, Yang Zhao, Grayson E. Rodriguez, Pingdong Tao, Matthias Obenaus, et al.antibodies were purchased from BioLegend: mouse CD45.2 (109839), CD3 (100206), CD4 (100453, 100430, 100428, 100451), CD8 (100706), NK1.1 (156506), TCRvα2 (127806, 127822), TCRvα3.2 (135404), Thy1.1 (202528, 202522),

(15) IL-21 enhances the cytotoxicity of intratumoral CD8+ T cells, improving radiation efficacyJCI InsightFebruary 23, 2026Xin-yang Li, Xue-qi Xie, Bao-chao Wei, Xiao-zheng Sun, Min-xin Chen, Ru-fei Liu, Qing-xu Tao, Yi-heng Huang, Qian Wang, Shuang-shuang Ma, et al.1100204/100233; 1:200, BD Biosciences, 552774), CD8 (1:200, BioLegend, 100730), CD4 (1:200, BioLegend, 100546/100451), CD11b (1:200, BioLegend, 117310), CD11c (1:200, BioLegend, 117349), CD19 (1:200, BioLegend, 115506),

(16) Radiation-Enhanced CD24 Membrane Trafficking via GPI Anchoring Mediates Antitumor Immune EvasionCancer ResJanuary 9, 2026Lingyi Kong, Minqi Zhou, Wenqian Yuan, Yijun Wang, Xixi Liu, Jiacheng Wang, Weidong Zhong, Qinyan Chen, Pengfei Li, Tingting Pu, et al.#157213, RRID: AB_2894427), CD3 (BioLegend, cat. #100245, RRID: AB_2565882), CD4 (BioLegend, cat. #100451, RRID: AB_2564591), and CD8 (BioLegend, cat. #100751, RRID: AB_2561389). Subsequently, cells were fixed

(17) Verteporfin-loaded hydrogel targeting YAP-mediated MDSCs recruitment for the treatment of residual tumors after incomplete radiofrequency ablationTheranosticsJanuary 1, 2026Jiawen Chen, Junfeng Liu, Xiaoting Zhang, Xi Li, Jinming Fan, Shengchao Zhao, Junbin Liu, Bin Zhou, Ke ZhangPE/Cy7-anti-CD206 (BioLegend, 141719), APC/Cy7-anti-CD3 (BioLegend, 100222), BV605-anti-CD4 (BioLegend, 100451), FITC-anti-CD8 (BioLegend, 553030), and PE-anti-Granzyme B (BioLegend, 372207). Flow cytometric analysis

(18) Pulsed 980 nm near-infrared photobiomodulation attenuates OVA-induced allergic asthma by modulating Th2 cytokine responses and inflammatory cell infiltrationScientific ReportsDecember 31, 2025Zhengyi Wu, Jia Zhang, Qingxiang Gao, Detian Wang, Yiping Zhao, Hong Yu, Shih-Chin ChengLive/Dead marker (Cat. 65-0865-14, Invitrogen), CD45 (Cat. 103147, Clone 30-F11, BioLegend), CD4 (Cat. 100451, Clone RM4-5, BioLegend), CD8 (Cat. 11–0081-85, Clone 53–6.7, eBioscience), CD11b (Cat. 48-0112-82,

(19) Organ-specific delivery of an mRNA-encoded bispecific T cell engager targeting glypican-3 in hepatocellular carcinomaNat CommunDecember 15, 2025Yan Huang, Shaoli Liu, Xiaoju Zhang, Bingxu Zhang, Feng Shi, Jia Zhang, Shuaibo Shao, Hongya Han, Xiaoyun Ma, Jing Xie, et al.staining buffer after washing using anti-mouse CD45-APC-Cy7 (Biolegend, 147718), CD4-BV605 (Biolegend, 100451), CD8a-PE (Biolegend, 100707), CD44-FITC (Biolegend, 156008), and CD62L-APC (Biolegend, 161218), TCR

(20) Notch3 destabilizes regulatory T cells to drive autoimmune neuroinflammation in multiple sclerosisImmunityNovember 11, 2025Mehdi Benamar, Paola Contini, Klaus Schmitz-Abe, Olga Lanzetta, Feven Getachew, Corinne Bachelin, Juan Manuel Leyva Leyva Castillo, Muyun Wang, Fatma Betul Oktelik, Océane Perrot, et al.1:300, Biolegend), Helios (22F6, catalogue no: 47–9883-42 1:200, Thermofisher, CD4 (GK1.5, catalogue no: 100451, 1:500, Biolegend), IL-17 (TC11–18H10.1, catalogue no: 506922, 1:200, Biolegend), CD45 (30-F11, catalogue

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(1)

7/28/2023Excellent Staining With CD4 Antibody From BioLegend Jordan ZhouGreat separation of the CD4 positive population from the negative when intestinal cells are stained with this antibody.
(1)

3/19/2019Brilliant Violet 605 Anti-Mouse CD4 AntibodyDr. Javier CasaresBrilliant Violet 605 Anti-mouse CD4 Antibody labels cardiac T helper cells.

Brilliant Violet 605™ anti-mouse CD4 from BioLegend

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Brilliant Violet 605™ anti-mouse CD4 from BioLegend

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