PSCA (7F5) Antibody sc-80654 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemPSCA (7F5) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-80654
Antibody TypePrimary Antibodies
NCBI Gene AliasesPRO232, lncPSCA
Clone7F5
Quantity200 µg/ml
ApplicationsWB, IF, IHC(P), FCM
Reactivityhuman
ClonalityMonoclonal
Hostmouse
Conjugate/TagUnconjugated
FormatPurified
NCBI Full Gene Nameprostate stem cell antigen
TargetPSCA
IsotypeIgG1

Questions and Answers

Can this antibody be used for Western blotting, and what has been documented regarding its effectiveness in this application?

Yes, the PSCA (7F5) Antibody has been shown to work effectively in Western blotting applications, as evidenced by its citation in 12 scientific articles. Researchers have utilized this antibody to detect the Prostate Stem Cell Antigen in various human samples.

I'm interested in using this antibody for immunohistochemistry. Are there any publications that support its use in this technique?

The PSCA (7F5) Antibody is suitable for immunohistochemistry, and its application has been documented in scientific literature. Researchers have successfully employed this antibody to visualize the Prostate Stem Cell Antigen in tissue sections, providing valuable insights into its expression patterns.

What species does this antibody react with, and is it specific to human samples?

This antibody is specifically reactive with Homo sapiens, meaning it is designed for use with human samples. Its specificity for human tissues makes it a valuable tool for studies focused on human biology and disease.

What is the clonality of this antibody, and how might that influence its performance in experiments?

The PSCA (7F5) Antibody is a monoclonal antibody, which typically provides high specificity and consistency in experimental results. Monoclonal antibodies are derived from a single clone of cells, ensuring that they recognize a single epitope on the target antigen, which can enhance the reliability of experimental outcomes.

Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) C-terminus CD28 phosphorylation (Y218) modulates IL-2 secretion and antitumor effect of CAR-T cellsbioRxivFebruary 6, 2026Elena Martinez-Planes, Maria Cecilia Ramello, Miguel G. Fontela, Mohammad-Reza Shokri, Lancia Darville, John Koomen, Youngchul Kim, Daniel Abate-Daga563795), rabbit ITK (Cell Signaling, 77215), anti-rabbit AF488(Cell Signaling 4412S), PSCA PE (Santa Cruz, sc-80654). Cytokine production To evaluate the ability of CAR-T cells to produce cytokines, we cocultured them

(2) Human anti-PSCA CAR macrophages possess potent antitumor activity against pancreatic cancerCell Stem CellJune 6, 2024Zahir Shah, Lei Tian, Zhixin Li, Lewei Jin, Jianying Zhang, Zhenlong Li, Tasha Barr, Hejun Tang, Mingye Feng, Michael A. Caligiuri, et al."FITC anti-human HLA-DR, DP, DQ Antibody",BioLegend,"Cat# 361705, RRID:AB_2563191" PE anti-PSCA (7F5) Antibody,Santa Cruz,"Cat# sc-80654, RRID:AB_1128761" "Pacific Blue™ anti-human HLA-A, B, C Antibody",BioLegend,"Cat# 311418, RRID:AB_493669" Pacific Blue™ anti-human CD66b

(3) Single-cell transcriptomics of human-skin-equivalent organoidsCell reportsMay 30, 2023Stabell AR, Lee GE, Jia Y, Wong KN, Wang S, Ling J, Nguyen SD, Sen GL, Nie Q, Atwood SX.Santa Cruz; sc-47697), rabbit anti-VIM (1:500; Cell Signaling; D21H3), mouse anti-PSCA (1:500; Santa Cruz; sc-80654), mouse anti-FLG (1:500; Santa Cruz; sc-66192), mouse anti-DSG1 (1:500; Santa Cruz; sc-137164), mouse

(4) Secreted Fas Decoys Enhance the Antitumor Activity of Engineered and Bystander T Cells in Fas Ligand-Expressing Solid TumorsCancer immunology researchNovember 2, 2022Bajgain P, Torres Chavez AG, Balasubramanian K, Fleckenstein L, Lulla P, Heslop HE, Vera J, Leen AM.on tumor cells was measured using anti-PSCA (Santa Cruz Biotechnology. Inc., Dallas, TX, catalog no. sc-80654) and anti-human CD178-APC (BD Biosciences, catalog no. 564262), respectively. CAR molecules were detected

(5) Helicobacter pylori shows tropism to gastric differentiated pit cells dependent on urea chemotaxisNature communicationsOctober 5, 2022Aguilar C, Pauzuolis M, Pompaiah M, Vafadarnejad E, Arampatzi P, Fischer M, Narres D, Neyazi M, Kayisoglu Ö, Sell T, et al.buffer (PBS + 10% FBS). Cells were incubated with anti-PSCA Alexa 647 conjugated antibodies (1:50, sc-80654, Santa Cruz Biotechnologies) for 30 min at 4 °C in dark. Cells were then washed twice and resuspended

(6) Single-cell transcriptomic analysis suggests two molecularly subtypes of intrahepatic cholangiocarcinomaNature communicationsMarch 28, 2022Song G, Shi Y, Meng L, Ma J, Huang S, Zhang J, Wu Y, Li J, Lin Y, Yang S, et al.(1:2000 dilution, ab223582, Abcam), S100P (1:3000 dilution, ab133554, Abcam), PSCA (1:2000 dilution, sc-80654, Santa Cruz Biotechnology); panel 4: CD45 (1:2500 dilution, ab40763, Abcam), CD3 (1:2000 dilution, ab16669,

(7) Proteomic Profiling of Two Distinct Populations of Extracellular Vesicles Isolated from Human Seminal PlasmaInternational journal of molecular sciencesOctober 26, 2020Zhang X, Vos HR, Tao W, Stoorvogel W.(clone 18, 610821, BD Biosciences, San Jose, California, USA, 1:1000); mouse anti-human PSCA (clone 7F5, sc-80654, Santa Cruz Biotechnology, Dallas, Texas, USA, 1:1000); mouse anti human Annexin A1 (clone 29, 610066,

(8) PSCA is a target of chimeric antigen receptor T cells in gastric cancerBiomarker researchJanuary 1, 2020Wu D, Lv J, Zhao R, Wu Z, Zheng D, Shi J, Lin S, Wang S, Wu Q, Long Y, et al.

(9) Novel PSCA targeting scFv-fusion proteins for diagnosis and immunotherapy of prostate cancerJournal of cancer research and clinical oncologyOctober 1, 2017Kessler C, Pardo A, Tur MK, Gattenlöhner S, Fischer R, Kolberg K, Barth S.

(10) Construction of a fusion plasmid containing the PSCA gene and cytotoxic T-lymphocyte associated antigen-4 (CTLA-4) and its anti-tumor effect in an animal model of prostate cancerBrazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicasOctober 24, 2016Mai TJ, Ma R, Li Z, Bi SC.the cells were treated with a FITC-labeled mouse anti-PSCA antibody (Santa Cruz Biotechnology, USA, sc-80654 FITC), as well as with a Phycoerythrin (PE)-labeled mouse anti-CTLA-4 (Santa Cruz Biotechnology, sc-376016

(11) Epithelial-to-mesenchymal transition leads to docetaxel resistance in prostate cancer and is mediated by reduced expression of miR-200c and miR-205The American journal of pathologyDecember 1, 2012Puhr M, Hoefer J, Schäfer G, Erb HH, Oh SJ, Klocker H, Heidegger I, Neuwirt H, Culig Z.

(12) Potential establishment of lung metastatic xenograft model of androgen receptor-positive and androgen-independent prostate cancer (C4-2B)UrologyOctober 1, 2012Yamamichi F, Matsuoka T, Shigemura K, Kawabata M, Shirakawa T, Fujisawa M.

(13) MRI of prostate stem cell antigen expression in prostate tumorsNanomedicine (London, England)May 1, 2012Ren J, Zhang Z, Wang F, Yang Y, Liu Y, Wei G, Yang A, Zhang R, Huan Y, Cui Y, et al.

(14) Prostate cancer targeting motifs: expression of αν β3, neurotensin receptor 1, prostate specific membrane antigen, and prostate stem cell antigen in human prostate cancer cell lines and xenograftsThe ProstateApril 1, 2012Taylor RM, Severns V, Brown DC, Bisoffi M, Sillerud LO.

(15) Identification of distinct populations of prostasomes that differentially express prostate stem cell antigen, annexin A1, and GLIPR2 in humansBiology of reproductionMarch 1, 2012Aalberts M, van Dissel-Emiliani FM, van Adrichem NP, van Wijnen M, Wauben MH, Stout TA, Stoorvogel W.

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8/6/2021Good Anti-PSCA Antibody Liyong Z.To confirm the specificity of PSCA antibody in 293, flow cytomery was used to detect the binding of PSCA and its antibody in PSCA stable cells compared to the parent cell control (blank) and secondary... Read Review

PSCA (7F5) Antibody

PSCA (7F5) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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PSCA (7F5) Antibody from Santa Cruz Biotechnology, Inc.

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