Ubiquitin (P4D1) Antibody sc-8017 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemUbiquitin (P4D1) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-8017
Antibody TypePrimary Antibodies
ApplicationsWB, IP, IF, IHC(P), FCM, ELISA
Reactivitymouse, rat, human
CloneP4D1
Quantity200 µg/ml
ClonalityMonoclonal
Conjugate/TagUnconjugated
Hostmouse
FormatPurified
NCBI Full Gene Nameribosomal protein S27A, ubiquitin A-52 residue ribosomal protein fusion product 1, ubiquitin C, ubiquitin B
TargetUbiquitin
NCBI Gene AliasesD8Ertd21e, 2700054O04Rik, Ubb2, Rps27a, Cep52, HEL-S-50, Uba52, 0610006J14Rik, Ubb, Ubc, Gm1863, TI-225
IsotypeIgG1

Questions and Answers

Can this ubiquitin antibody be used in Western blotting for detecting ubiquitin modifications in various cell types?

Yes, the Ubiquitin (P4D1) Antibody has been successfully utilized in Western blotting to detect ubiquitin modifications in various studies, including those involving mouse mammary epithelial cells and human oral squamous carcinoma cells, demonstrating its effectiveness in different experimental contexts.

Is this antibody suitable for use in immunoprecipitation assays?

The Ubiquitin (P4D1) Antibody has been employed in immunoprecipitation assays, as indicated in studies that investigated protein interactions and ubiquitination processes, confirming its utility in this application.

What species can this antibody react with, and has it been cited in relevant research?

This antibody is reactive with mouse, human, and rat species. It has been cited in over 3100 scientific articles, indicating its widespread use and relevance in various research fields.

Has this antibody been used in any studies related to cancer research?

Yes, the Ubiquitin (P4D1) Antibody has been referenced in cancer research, including studies on the regulation of oncogenes and tumor growth, such as the investigation of Notch signaling in breast carcinomas and the role of ubiquitination in T-cell leukemia, highlighting its significance in cancer biology.

Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Oxidative stress causes a reversible decrease of deubiquitylases activity in old vertebrate brainsNat CommunApril 21, 2026Amit Kumar Sahu, Alberto Minetti, Domenico Di Fraia, Antonio Marino, Patrick Rainer Winterhalter, Daniela Giustarini, Ranieri Rossi, Andreas Simm, Francesco Neri, Federico Galvagni, et al.roller (BioCote® Stuart® SRT6) with primary antibodies against total ubiquitin P4D1 (1:1000, Santa Cruz #sc8017), Lys-48 specific anti-ubiquitin antibody (1:1000, Sigma Aldrich #05-1307), NRF2 (1:2000, Proteintech

(2) Targeting of Itch by Clomipramine or Gene Therapy improves cognitive defects related to Alzheimer's DiseaseiScienceApril 17, 2026Monika Chauhan, Komal Singh, Pushkar Sharmafor WB, 1:100 for IHC), NeuN (Novus, cat. no. NBP2-67314; 1:100 for IHC), Ubiquitin (Santa cruz, cat. no. sc-8017; 1:1000 for WB) and β-Actin (Santa cruz, cat. no. sc-47778, 1:2000 for WB). Quantification and statistical

(3) SplitTurboID mapping of dimeric protein phosphatase complex interactomesiScienceApril 17, 2026Abishankari Rajkumar, Antoine Gaudreau-Lapierre, Curtis L.F. Anthony, Vincent Nguyen, Sarah Ooi, Denise Campuzano, Laura Trinkle-MulcahyAB_2105785 Rabbit anti-APPBP2,Novus,Cat#NBP2-81781; RRID:AB_3415535 Monoclonal mouse anti-Ubiquitin,Santa Cruz,Cat#sc-8017; RRID:AB_628423 Monoclonal mouse anti-SC35,Abcam,Cat#ab11826; RRID:AB_298608 Rabbit Anti-Goat IgG (H + L)-FITC

(4) Loss of ZNRF3/RNF43 Unleashes EGFR in CancerElifeApril 10, 2026Fei Yue, Amy T Ku, Payton D Stevens, Megan N Michalski, Weiyu Jiang, Jianghua Tu, Zhongcheng Shi, Yongchao Dou, Yi Wang, Xin-Hua Feng, et al.(Cell Signaling Technology, 2278), Flag-tag M2 mouse antibody (Sigma-Aldrich, F1804), Ub (P4D1) mouse antibody (Santa Cruz, sc-8017), CBL mouse antibody (Santa Cruz, sc-1651), non-phospho (Active) β-catenin (Ser33/37/Thr41) (D13A1)

(5) Arsenic-Induced PPARγ, with the Coordinated Action of p62, Inhibits Apoptosis and Necroptosis and Activates the DNA Damage Response in A549 Lung Cancer Cells, Leading to CarcinogenesisCellsApril 8, 2026Hak-Ryul Kim, Seon-Hee OhSQSTM1/p62 (sc-25575), Fas (sc-7886), p53 (sc-126), RIP3 (sc-374639), p21 (sc-6246), and K48-ubiquitin (sc-8017), as well as rhodamine-conjugated goat anti-rabbit (sc-2091) and FITC-conjugated goat anti-mouse (sc-2010)

(6) Cullin-3 adaptor SHKBP1 inhibits SQSTM1/p62 oligomerization and Keap1 sequestrationJ Cell BiolApril 6, 2026Lin Luan, Xiaofu Cao, Zijun Xia, Shivanshi Vaid, Manuel D. Leonetti, Jeremy M. BaskinSanta Cruz Biotechnology (sc-390121, RRID unavailable); mouse anti-ubiquitin, Santa Cruz Biotechnology (sc-8017, RRID:AB_628423); mouse anti-GFP, Santa Cruz Biotechnology (sc-9996, RRID:AB_627695); mouse anti-mCherry,

(7) Viperin weakens IFN-I-induced immune activity by facilitating STAT1 degradation through E3 ligase UBE4ACell InsightApril 3, 2026Ying Miao, Yukang Yuan, Liping Qian, Yong Yu, Qun Cui, Tingting Zhang, Renxia Zhang, Qian Zhao, Zhize Li, Anning Miao, et al.1:1 000), HA (Sigma, ab9110, 1:5 000), UBE4A (Santa Cruz, sc-365904, 1:1 000), Ubiquitin (Ub) (Santa Cruz, sc-8017, 1:500), 48ub (Cell Signaling, #4289, 1:500), 63ub (Millipore, #05-1308, 1:500), ITCH (Selleck, F0891,

(8) Specificity and recognition of the ADP-ribosyl-ubiquitin modification in the DNA damage responsePLoS BiolApril 2, 2026Chatrin Chatrin, Kang Zhu, Michael D. R. Simmons, Lucy Maginn, Kira Schützenhofer, Yang Lu, Nina Đukić, Sven Wijngaarden, Max S. Kloet, Katarzyna Wiktoria Kliza, et al.membrane was incubated with primary antibodies: mouse monoclonal anti-Ub (P4D1) (Santa Cruz Biotechnology sc- 8017), poly/mono-ADP ribose (D9P7Z) rabbit mAb (Cell Signaling Technology #89190), overnight at 4 °C followed

(9) The E3-ome gene-centric compendium reveals the human E3 ligase landscapeCellApril 2, 2026Ngee Kiat Chua, Tania J. González-Robles, Cameron J. Reddington, Jane Dudley-Fraser, Richard W. Birkinshaw, Jiru Han, Ashleigh Solano, Soon Wei Wong, Tomasz Kochańczyk, Joshua J. Peter, et al.RESOURCE,SOURCE,IDENTIFIER Antibodies,Antibodies,Antibodies ,, Anti-ubiquitin antibody,Santa Cruz Biotechnology,Cat# sc-8017: RRID: AB_62842 Peroxidase AffiniPure® Goat Anti-Mouse IgG (H+L),Jackson ImmunoResearch,Cat# 115-035-003:

(10) IFI35 suppresses the transcription of hepatitis B virus cccDNA minichromosome via promoting HNF4α proteasomal degradationJ Biomed SciMarch 30, 2026Nayeon Kim, Jae Jin Shin, Jae Won Oh, Juhee Won, Ah Ram Lee, Mehrangiz Dezhbord, Jeongwoo Park, Ki-Young Lee, Dong-Sik Kim, Kwang Pyo Kim, et al.°C. The levels of polyubiquitination were analyzed by Western blotting with anti-Ubiquitin antibody (sc-8017, Santa Cruz). HBV virion production and infection. HBV virions (genotype D) were isolated and concentrated

(11) Deciphering the STAT3-PXN positive feedback loop in GBM, IDH-wildtype: transcriptional regulation and inhibition of YB-1 ubiquitinationCell Death DiscoveryMarch 23, 2026Xiaodong Li, Hongyan Guo, Ziyi Liu, Tianze Wang, Maode Wang, Wei Chen, Hai Yu(cat. no. sc-101198).Anti-Ubiquitin primary antibody (P4D1) was purchased from Santa Cruz (cat. no. sc-8017).Anti-GAPDH primary antibody was purchased from CST (cat. no. #3683).Anti-beta Actin antibody was purchased

(12) Myofibrillar protein accumulation but reduced protein synthesis in PDCD4-depleted myotubesPLoS OneMarch 19, 2026Stephen Mora, Lilia Alihemmat, Logan D. Davari, Termeh Ataie, Parsa Nafari Mehranjani, Luke Flewwelling, Arthur J. Cheng, Olasunkanmi A. J. Adegoke(MuRF1, #55456-1-AP) was obtained from Protein Tech (San Diego, CA, USA). Anti-ubiquitin antibody (#sc-8017) was purchased from Santa Cruz Technology (Dallas, TX, USA) while antibodies against γ-tubulin (#T6557),

(13) Dual ubiquitin signalling by SLOMO controls AUX1 activity and turnover during root gravitropismThe EMBO JournalMarch 17, 2026Lixia Pan, Shanshuo Zhu, Shao-Li Yang, Nathan Mellor, Francesca R Iacobini, Tingyu Zhu, Pia Neyt, Brigitte van de Cotte, Michaël Vandorpe, Ranjan Swarup, et al.130-131-646 α-HA,abcam,Cat# ab1190 α-AUX1,Agrisera,Cat# AS16 3957 α-RFP,ChromoTek,Cat# 6g6 α-P4D1,Santa Cruz,Cat# sc-8017 α-Mouse,Sigma-Aldrich,Cat# A9044 Anti-Goat,Agilent Dako,Cat# P0449 α-Tubulin,Sigma-Aldrich,Cat# T5168 GFP-Trap®_MA,Chromotek,Cat#

(14) Paneth cell SIRT1 deficiency increases intestinal stress resistance by modulating the gut microbiotaEMBO ReportsMarch 13, 2026Liz M Garcia-Peterson, Alicia S Wellman, Xiaojiang Xu, Ming Ji, Caroline Duval, Igor Shats, Xiaoyue Wu, Thomas A Randall, Hamed Bostan, David Cunefare, et al.AF700,eBioscience™,56-0042-82 GAPDH,Cell Signaling,2118 ACTIN,"EMD,Millipore",MAB1501 SIRT1,Cell Signaling,2310 Ubiquitin,Santa Cruz,sc-8017 ATF4,Cell Signaling,11815 Acetylated-Lysine,Cell Signaling,9814 β-catenin,Cell Signaling,8480 β-catenin,GeneTex,GTX101435 β-catenin

(15) Heart-Specific and Conditional Deletion of the Immt Gene Reveals Its Role in Regulating Mitochondrial Structure and Total Heart MetabolismCellsMarch 12, 2026Yasuhide Kuwabara, Caitlin Keezer, Suh-Chin J. Lin, Akanksha Rajput, Jeffery D. Molkentinanti-MFN2 (#9482, Cell Signaling Technology, 1:1000), anti-MFN1 (#ab104274, abcam, 1:750), anti-Ubiquitin (#sc-8017, Santa Cruz, Dallas, TX, USA, 1:200), anti-GAPDH (#10R-G109A, Fitzgerald, Acton, MA, USA, 1:5000), anti-Mic26

(16) Sirt1 coordinates the mitochondrial UPR and myocellular proteostasis to preserve muscle integrity during muscle atrophy in zebrafishFront Cell Dev BiolMarch 11, 2026Qing Chen, Yu-Lun Chang, Miao-Wen Hung, Po-Lin Lee, Chen Hsin, Yi-Fan LinTween-20 (PBST) for 1 h, before blotting in the primary antibodies (Ubiquitin, Santa Cruz Biotechnology, SC-8017, 1:1,000; beta-Tubulin, Affinity Biosciences, T0034, 1:5,000). ECL chemiluminescence was used for signal

(17) The compound LY295427 antagonizes 25-hydroxycholesterol through binding to INSIGJournal of Lipid ResearchMarch 6, 2026Xing-Yan Wen, De-Jie Zhang, Li-Ming He, Ming Sun, Qi Jiang, Ying Zhu, Bao-Liang Song, Wen-Wei Qiu, Xiao-Yi Lumonoclonal antibody against HA-tag (#H3663; Sigma), mouse monoclonal antibody P4D1 against ubiquitin (#SC-8017; Santa Cruz Biotechnology), mouse monoclonal antibody 9D5 against SCAP (#CRL-2347; ATCC), mouse monoclonal

(18) Poly(ADP-ribose) glycohydrolase enforces p21 degradation via dePARylation to promote gastric cancer progressionJournal of Clinical InvestigationMarch 2, 2026Yangchan Hu, Qimei Bao, Yixing Huang, Yan Wang, Xin Zhao, Junjun Nan, Yuxin Meng, Mingcong Deng, Yuancong Li, Zirui Zhuang, et al.purchased from Abcam. Anti-Myc (#10015-M01, 1:1000) antibody was purchased from MabStar. The anti-Ub (#SC-8017, 1:1000) antibody was purchased from Santa Cruz. Anti-GFP (#YM8341, 1:5000) was purchased from Immunoway.

(19) TBK1 Induces the Formation of Optineurin Filaments That Condensate with Polyubiquitin and LC3 for Cargo SequestrationAdvanced ScienceMarch 1, 2026Maria G. Herrera, Lena Kühn, Lisa Jungbluth, Verian Bader, Laura J. Krause, David Kartte, Elias Adriaenssens, Sascha Martens, Jörg Tatzelt, Carsten Sachse, et al.anti‐ Optineurin,Merck,"Cat# HPA003279, RRID:AB_1079527" Mouse monoclonal anti ubiquitin,Santa Cruz,"Cat# sc‐8017, RRID:AB_628423" Mouse monoclonal anti‐HA,BioLegend,"Cat# 901502, RRID: AB_2565007" Rabbit Phospho‐Optineurin

(20) USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring MiceAdvanced ScienceMarch 1, 2026Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, et al.Ltd. (Wuhan, China). The antibodies of NOBOX (No. sc‐514178), HIF1α (No. sc‐13515), and Ubiquitin (No. sc‐8017) were purchased from SANTA CRUZ BIOTECHNOLOGY, INC. (Wuhan, China). All the primers were synthesized

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(1)

9/23/2022Anti-Ubiquitin Antibody Works Very Well Liyong Z.HEK293T cells stably expressing control (Ctrl) or USP20 shRNAs were transfected with the indicated constructs. After 48 h, cells were treated with MG132 for 6 h before collecting. IP with Flag-tagged ... Read Review
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6/10/2022Good Ubiquitin Antibody for Western Blot Chang Seok LeeA mouse model with I4895T mutation in type1 ryanodine receptor displays muscle weakness and atrophy. Muscle of this mutant model showed decreased SR Ca2+ transient, decreased cytosolic Ca2+, increased... Read Review
(1)

2/5/2018Pan Ubiquitin Antibody (For Western Blot) Andrea EstradaThis antibody was used to examine the effects of various nutrient treatments on protein ubiquitination in H4IIE whole cell lysates. This antibody was compared to several other TUBE (tandem ubiquitin ... Read Review
(1)

12/14/2016Ubiquitin Antibody For Detection Of Poly-Ubiquitinated Proteins Claire StewartThe ubiquitin proteasome system is critical for maintaining cellular health and defects in the system can result in pathogenesis of many diseases. Ubiquitination is a post translational modification ... Read Review
(1)

7/14/2015Great anti-Ubiquitin antibody for total cell lysate Nico MeyerWe analyze sample of crude Arabidopsis thaliana (mouse-ear cress) protein extract from seedlings or later developmental stages according to their protein content. This antibody recognizes the ... Read Review

Ubiquitin (P4D1) Antibody

Ubiquitin (P4D1) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Ubiquitin (P4D1) Antibody from Santa Cruz Biotechnology, Inc.

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