GAD2 antibody 198 104 from Synaptic Systems GmbH

Product Specs
ItemGAD2 antibody
CompanySynaptic Systems GmbH
Price $375.00Supplier Page View Company Product Page
Catalog Number198 104
Clonalitypolyclonal
ImmunogenRecombinant protein corresponding to AA 3 to 96 from mouse GAD2
Antibody TypePrimary antibody
Formatlyophilized
Quantity100 µl
Reactivityhuman, rat, mouse
HostGuinea pig
ApplicationsWB, IP, ICC, IHC, IHC-P
TargetGAD2

Questions and Answers

Can this GAD2 antibody be used for immunofluorescence in my neuronal studies?

Yes, the GAD2 antibody has been utilized in immunofluorescence applications as demonstrated in various studies, including those investigating GABAergic neuron activity and synaptic structures in the brain (; ).

Is this antibody effective for Western blotting in detecting GAD65 levels?

The GAD2 antibody has been shown to work effectively in Western blotting for detecting GAD65 levels, as referenced in multiple studies where it was used to analyze protein expression in neuronal tissues (; ).

What species can I expect this antibody to react with in my experiments?

The GAD2 antibody is reactive with mouse, human, and rat tissues, making it suitable for studies involving these species (; ).

Are there any specific applications where this antibody has been cited in the literature?

The GAD2 antibody has been cited in various applications including Western blotting, immunocytochemistry, and immunohistochemistry, particularly in studies focusing on GABAergic signaling and synaptic plasticity (; ).

Synaptic Systems GmbH

Rudolf-Wissell-Str. 28

Goettingen 37079

Germany

Phone: +49-551-50556-0
+49-551-50556-384

Company Profile

Website: http://www.sysy.com/

(1) ATP Synthase Abundance in Neuronal Extracellular Vesicles Reflects Changes in the Mitochondria of Parent NeuronsJournal of extracellular vesiclesAugust 1, 2025Yao PJ, Nogueras-Ortiz C, Pucha KA, Kapogiannis D.Ab (188004, Synaptic Systems), mouse anti‐synaptophysin Ab (S5768, Sigma), guinea pig anti‐GAD Ab (198104, Synaptic Systems), rabbit anti‐cFos Ab (2250, Cell Signaling), rabbit anti‐biotin Ab (5597, Cell Signaling),

(2) Chronic benzodiazepine treatment triggers gephyrin scaffold destabilization and GABAAR subsynaptic reorganizationFront Cell NeurosciJuly 4, 2025Caitlyn A. Chapman, Nadya Povysheva, Tyler B. Tarr, Jessica L. Nuwer, Stephen D. Meriney, Jon W. Johnson, Tija C. JacobmAb7a,Rabbit,Synaptic Systems,Cat# 147 018 RRID:AB_2651176,"1/1,000",PLA,3 GAD65,Guinea pig,Synaptic Systems,Cat# 198 104 RRID:AB_10557995,1/500,IF,5 VGAT,Guinea pig,Synaptic Systems,Cat# 131 004 RRID:AB_887873,"1/1,000",DNA-PAINT,2 VGAT,Guinea pig

(3) Laminar-Specific Alterations in Calbindin-Positive Boutons in the Prefrontal Cortex of Subjects With SchizophreniaBiological PsychiatryJuly 1, 2023Kenneth N. Fish, Brad R. Rocco, James D. Wilson, David A. LewisUSA",product # AF2086,Lot KRD0110031 Antibody,GAD65 (guinea pig host; 1:500),Synaptic Systems,product # 198104,Lot 3

(4) Control of contextual memory through interneuronal α5-GABA(A) receptorsPNAS NexusApril 1, 2023Zhu M, Abdulzahir A, Perkins MG, Chu CC, Krause BM, Casey C, Lennertz R, Ruhl D, Hentschke H, Nagarajan R, et al.anti-GABRA5 (1:200, Origene Cat# TA338505), and guinea pig polyclonal anti-GAD2 (1:200, Synaptic Systems Cat# 198 104) overnight at 4°C in a moist chamber with constant agitation (100 rpm)]. Slices were then washed three

(5) Cerebrospinal fluid-contacting neuron tracing reveals structural and functional connectivity for locomotion in the mouse spinal cordeLifeFebruary 21, 2023Nakamura Y, Kurabe M, Matsumoto M, Sato T, Miyashita S, Hoshina K, Kamiya Y, Tainaka K, Matsuzawa H, Ohno N, et al.

(6) The neuropeptide PACAP alleviates T. gondii infection-induced neuroinflammation and neuronal impairmentJ NeuroinflammationNovember 19, 2022Caio Andreeta Figueiredo, Henning Peter DÃ¼sedau, Johannes Steffen, Stefanie Ehrentraut, Miklos P. Dunay, Gabor Toth, Dora ReglÃ¶di, Markus M. Heimesaat, Ildiko Rita Dunayprimary antibodies in the same blocking solution. Accordingly, GAD65 (Synaptic System, SYSY, Germany, #198,104, 1:1000), GAD67 (SYSY, #198,211, 1:500), TrkB (CST, #4603, 1:1000), beta-III-Tubulin (Sigma, #T8660,

(7) GABA facilitates spike propagation through branch points of sensory axons in the spinal cordNature neuroscienceOctober 1, 2022Hari K, Lucas-Osma AM, Metz K, Lin S, Pardell N, Roszko DA, Black S, Minarik A, Singla R, Stephens MJ, et al.anti-Myelin Basic Protein (MBP) (1:200; ab106583, Abcam, Cambridge, UK), guinea pig anti-GAD2/GAD65 (1:500; 198 104; Synaptic Systems); chicken anti-VGAT (1:500; 131 006, Synaptic Systems, Goettingen, Germany), rabbit

(8) Overexpression of Neuregulin-1 Type III Has Impact on Visual Function in MiceInternational journal of molecular sciencesApril 19, 2022Su N, Zhang W, Eter N, Heiduschka P, Zhang M.No.,Dilution Kv-2.1,Rabbit,,Synaptic Systems,231 002,1:500 GAD 2/GAD 65,Guinea pig,,Synaptic Systems,198104,1:500 Neuregulin-1,Rabbit,,GeneTex,GTX133355,1:1000 PSD-95,Rat,,Santa Cruz Biotechnology,sc-32290,1:300 Secondary

(9) Nrg1 haploinsufficiency alters inhibitory cortical circuitsNeurobiology of diseaseSeptember 1, 2021Navarro-Gonzalez C, Carceller H, Benito Vicente M, Serra I, Navarrete M, Domínguez-Canterla Y, Rodríguez-Prieto Á, González-Manteiga A, Fazzari P.

(10) Altered Parvalbumin Basket Cell Terminals in the Cortical Visuospatial Working Memory Network in SchizophreniaBiological psychiatryJuly 1, 2021Fish KN, Rocco BR, DeDionisio AM, Dienel SJ, Sweet RA, Lewis DA.USA",product # AF2086,Lot KRD0110031 Antibody,GAD65 (guinea pig host; 1:500),Synaptic Systems,product # 198104,Lot 3

(11) Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic ReticulumNeuronJanuary 20, 2021Kuijpers M, Kochlamazashvili G, Stumpf A, Puchkov D, Swaminathan A, Lucht MT, Krause E, Maritzen T, Schmitz D, Haucke V.(mouse),Enzo Life Sciences,"Cat# BML-PW8810 0500, RRID:AB_2051891" GAD65 (guinea pig),Synaptic Systems,"Cat# 198104, RRID:AB_10557995" GFAP (mouse),Sigma-Aldrich,"Cat# G3893, RRID:AB_477010" GluA1 (rabbit),Millipore,"Cat#

(12) Acid Sphingomyelinase Impacts Canonical Transient Receptor Potential Channels 6 (TRPC6) Activity in Primary Neuronal SystemsCellsNovember 18, 2020Stefanie Zeitler, Fabian Schumacher, Juliana Monti, Daniela Anni, Debarpan Guhathakurta, Burkhard Kleuser, Kristina Friedland, Anna Fejtová, Johannes Kornhuber, Cosima Rheinsolution (3% (v/v) FCS in PBS 1x): MAP 2 ms (Sigma #M4403, 1:1000), GAD 2/65 gp (Synaptic Systems #198104, 1:500; Synaptic Systems GmbH, Göttingen, Germany), pCREB rb (Ser133) (CST #9198, 1:1000; Cell Signaling

(13) "Optogenetic ""low-theta"" pacing of the septohippocampal circuit is sufficient for spatial goal finding and is influenced by behavioral state and cognitive demand"HippocampusNovember 1, 2020Mouchati PR, Kloc ML, Holmes GL, White SL, Barry JM.

(14) Assemblies of Perisomatic GABAergic Neurons in the Developing Barrel CortexNeuronJanuary 8, 2020Modol L, Bollmann Y, Tressard T, Baude A, Che A, Duan ZRS, Babij R, De Marco García NV, Cossart R.anti-GABA,Sigma-Aldrich,Cat#: A2052; RRID:AB_477652 Guinea pig polyclonal anti-GAD2,Synaptic Systems,Cat#: 198104; RRID: AB_10557995 Guinea pig polyclonal anti-VGluT2,Merck Millipore,Cat#: AB2251-I; RRID:AB_2665454 Mouse

(15) GABA bouton subpopulations in the human dentate gyrus are differentially altered in mesial temporal lobe epilepsyJournal of neurophysiologyJanuary 1, 2020Alhourani A, Fish KN, Wozny TA, Sudhakar V, Hamilton RL, Richardson RM.

(16) Early Sociability and Social Memory Impairment in the A53T Mouse Model of Parkinson's Disease Are Ameliorated by Chemogenetic Modulation of Orexin Neuron ActivityMolecular neurobiologyDecember 1, 2019Stanojlovic M, Pallais Yllescas JP Jr, Vijayakumar A, Kotz C.

(17) The X-Linked Intellectual Disability Gene Zdhhc9 Is Essential for Dendrite Outgrowth and Inhibitory Synapse FormationCell reportsNovember 19, 2019Shimell JJ, Shah BS, Cain SM, Thouta S, Kuhlmann N, Tatarnikov I, Jovellar DB, Brigidi GS, Kass J, Milnerwood AJ, et al.

(18) Mechanism and effects of pulsatile GABA secretion from cytosolic pools in the human beta cellNature metabolismNovember 1, 2019Menegaz D, Hagan DW, Almaça J, Cianciaruso C, Rodriguez-Diaz R, Molina J, Dolan RM, Becker MW, Schwalie PC, Nano R, et al.N-term110 (Christiane Hampe Lab), rb-α-GAD65 (Synapic Systems #198102), gp-α-GAD65 (Synaptic Systems #198104), rb-α-TauT (Sigma-Aldrich #HPA015028), rb-α-VGAT Oyster 650-labeled (Synaptic Systems #131103C5), rb-α-synaptophysin

(19) Regulation of dendrite morphology and excitatory synapse formation by zDHHC15Journal of cell scienceJuly 5, 2019Shah BS, Shimell JJ, Bamji SX.(Synaptic Systems, Göttingen, Germany #147011, 1:500), anti-GAD65 (Synaptic Systems, Göttingen, Germany #198104, 1:500), anti-GFAP (Synaptic Systems, Göttingen, Germany #173004, 1:400), anti-MAP2 (Millipore, Burlington,

(20) Diazepam Accelerates GABA_AR Synaptic Exchange and Alters Intracellular TraffickingFrontiers in cellular neuroscienceJanuary 1, 2019Lorenz-Guertin JM, Bambino MJ, Das S, Weintraub ST, Jacob TC.(Tocris Bioscience). Primary antibodies: rabbit GAPDH (WB) (14C10, Cell Signaling); guinea pig GAD-65 (IF) (198104, Synaptic Systems); rabbit γ2 GABAAR subunit (IF, WB, and IP) (224003, Synaptic Systems); rabbit gephyrin

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2/28/2023GAD655 Immunofluorescence-Cultured Neuron Bhavin ShahThis antibody was used to label the proportion of inhibitory neurons from hippocampal neuronal cultures.

GAD2 / GAD65 antibody

GAD2 / GAD65 antibody

GAD2 / GAD65 antibody

GAD2 / GAD65 antibody

GAD2 antibody from Synaptic Systems GmbH

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Synaptic Systems GmbH

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GAD2 antibody from Synaptic Systems GmbH

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