DNase II, also known as deoxyribonuclease II, is an enzyme that catalyzes the hydrolysis of phosphodiester bonds in DNA. An endonuclease with an optimal pH at 4.5-5 in vitro and a molecular weight of 38 kDa, it can act on both native and denatured DNA, yielding products with 3'-phosphates and 5'-hydroxyl ends. DNase II can usually be found in lysosomes, where it helps in degrading DNA during apoptosis and erythropoiesis. DNase is believed to have three phases of action: creating multiple nicks in the phosphodiester backbone of DNA, production of acid-soluble nucleotides, and reduction of oligonucleotides. DNase II has been used in molecular biology as a component of digestion mixes. Visit the supplier page for more enzyme information.
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- Deoxyribonuclease II is a glycoprotein endonuclease with a dimeric structure. Deoxyribonuclease II from porcine spleen ...
- 20000 Units
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- DNase II, Porcine Pancreas, >12000 Kunitz U/MG. Grade: Biotechnology. Storage: -20°C
- 20KU
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Novus Biologicals, a Bio-Techne Brand
- Solution. Purified
- 2000 Units
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- Lyophilized. Dialyzed. Purified
- 20000 Units
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Worthington Biochemical Corporation
- A dialyzed, lyophilized powder
- 80 ku
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Worthington Biochemical Corporation
- Chromatographically purified in a modification of the procedure of Bernardi et al., Biochim. Biophys. Acta, 129, 1 (1966...
- 20 ku
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Worthington Biochemical Corporation
- Chromatographically prepared. A solution in 50% glycerol
- 2 ku
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Worthington Biochemical Corporation
- Chromatographically prepared. A solution in 50% glycerol
- 5 ku
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Worthington Biochemical Corporation
- A dialyzed, lyophilized powder
- Bulk
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Worthington Biochemical Corporation
- Chromatographically purified in a modification of the procedure of Bernardi et al., Biochim. Biophys. Acta, 129, 1 (1966...
- Bulk
- Inquire
Worthington Biochemical Corporation
- Chromatographically prepared. A solution in 50% glycerol
- Bulk
- Inquire
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