Membrane Potential Assay Kits

Membrane potential assay kits are available from several suppliers to determine crucial changes in the electrochemical potential of membranes. Membrane potential is a hallmark of normal cellular functions, such as in mitochondrial energy generation and neuronal cell signal transmission. Damage to the mitochondrial membrane induces signaling pathways for apoptosis and therefore, this disruption in membrane potential acts as an early indicator of both apoptosis and pathological conditions. Membrane potential assay kits that use the cationic dye TMRE label active mitochondria, displaying a bright orange/red fluorescence in healthy cells, while showing reduced, diffuse fluorescence in apoptotic cells. Membrane potential assay kits can be used to indicate the health of cells, to study the effect of certain drugs on cells, and as preliminary indicators of pathological conditions. Visit the membrane potential assay kit suppliers for more details, including kit components.