
With the wide variety of tools currently available and in the works, scientists can assess apoptosis in individual and populations of cells, in samples from live animals to formalin fixed and paraffin embedded (FFPE) microtome slices. Light or fluorescent microscopes, flow cytometers, or spectrophotometers are used for assay detection, and to interrogate parameters ranging from RNA and protein expression, to histone modification, to plasma membrane phospholipid orientation, to membrane potential. The study of apoptosis' defective processes have been associated with a variety of diseases such as cancer. Assay can be outsourced to service facilities or brought in house with custom reagents or pre-made apoptosis assay kits.
New technologies are improving accuracy and speed.
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The revolutionary MACSima™ Platform streamlines your spatial biology research from end to end, reducing experimental workload and generating impactful data in no time. At its core is the fully automated MACSima™ System, which utilizes fluorescence ...
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Measure and assess your cell cultures with ease. Our Millicell® DCI Digital Cell Imager enables more efficient execution of the repetitive daily techniques associated with cell passaging. Quickly and objectively assess confluency, morphology, ...
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I am using apo one caspase assay kit and it is a very good product and I got good results.
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In this review we evaluate an easy-to-use flow-cytometry-based detection method for apotosis. We use this for a first screening of cell-culture cells.
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