RNase Inhibitor, Murine from New England Biolabs

Product Specs
ItemRNase Inhibitor, Murine
CompanyNew England Biolabs
Price $77.00 Inquire
Catalog NumberM0314S
Quantity3000 units
ApplicationsFunctional Genomics
Concentration40,000 U/mL
SourceAspergillus
Temperature-20 C

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New England Biolabs

240 County Road

Ipswich, Massachusetts 1938

United States

Phone: 800-632-5227
800-632-7799
978-921-1350

Company Profile

Website: http://www.neb.com

(1) A DNA-guided prokaryotic argonaute enables programmable RNA cleavage for sequencing and quality control of in vitro-transcribed RNAsMolecular Therapy Nucleic AcidsSeptember 8, 2026Lizhi Liu, Eric A. Hunt, Eric J. Wolf, Ivan R. Corrêa, Erbay Yigit, Sebastian GrünbergThermoPol reaction buffer, 30% glycerol, 160 units of Murine RNase Inhibitor (New England Biolabs, #M0314S), 67.4 pmol Mpa Ago, and 66.4 pmol guide (A1:/5Phos/ATCTCCTTCTTAAAGT, A1.2:/5Phos/TCCTTCTTAAAGTTAAAC,

(2) Detection of mutant cancer-derived circRNAs in extracellular vesicles by rolling circle amplificationMol Ther Nucleic AcidsSeptember 8, 2026Mikołaj Piotr Zaborowski, Charles Pin-Kuang Lai, Alessandro Sammarco, Bence György, Xuan Zhang, Kyungheon Lee, Young Jeong Na, Lorenzo Ceppi, Koen Breyne, Elizabeth Marie Champagne, et al.(20U/1 μL, Epicentre cat. no. RNR07250), 0.25 μL ribonuclease inhibitor (New England Biolabs, cat. no. M0314S) in 1 μL 10X reaction buffer and nuclease-free water (total volume 10 μL) for 1 h in 37°C. Water was

(3) Granular component sub-phases direct ribosome biogenesis in the nucleolusMol CellAugust 6, 2026Priyanka Dogra, Mylene C. Ferrolino, Suparna Khatun, Qi Miao, Michele Tolbert, Aaron Pitre, Shondra M. Pruett-Miller, Swarnendu Tripathi, David W. Baggett, Jaison John, et al.Tris-HCl, pH 7.5, 130 mM KCl, 2.35 mM MgCl2, 0.5% Triton X-100, 1 mM DTT, 200 U/ml RNase inhibitor [NEB, M0314], and protease inhibitor cocktail [Thermo Fisher, 78425]). The lysate was centrifuged at 12,000 × g

(4) RAPID: evaluation of Cas12a protospacer nicking and chimeric reporters for PAM-independent RNA and DNA diagnosticsNucleic Acids ResAugust 4, 2026Idorenyin A Iwe, Frank X Liu, Ariel Corsano, Severino Jefferson Ribeiro da Silva, Jennifer Doucet, Serena Singh, Gabriel Lamothe, Riham Zayani, Jessica Nguyen, Quinn Matthews, et al.(#M0653T), Cas12 diluent (#B0653A), Cas12 reaction buffer (NEBuffer™ r2.1, #B6002S), and RNase inhibitor (#M0314L) were purchased from New England Biolabs (NEB). Magnesium chloride solution (#7786303) was obtained

(5) Cytosolic and ER-associated ribosomes share rRNA 2'-O-methylation landscapes across human cell typesRNAAugust 1, 2026Ülkü Uzun, Anders H. Lund1 mM DTT, EDTA-free protease inhibitor cocktail [Roche, 11873580001], murine RNase inhibitor [NEB, M0314], and cycloheximide [100 µg/mL final; Sigma-Aldrich, C7698]) as described below. Digitonin stock was

(6) Honeydew: A Fluorescent Aptamer for Low-Cost Azo Food DyesChembiochemJuly 29, 2026Joseph M. Heili, Paul H. Mroch, Tanner G. Hoog, Orion M. Venero, Grace M. Gustafson, Katarzyna P. Adamala, Aaron E. EngelhartDTT, 8 mM GTP, 4 mM each of ATP, UTP, and CTP, 1 μM T7 RNAP, 0.4 units/μL RNase Inhibitor Murine (NEB, M0314L), and 0.02 units/μl inorganic pyrophosphatase (Milipore Sigma, I5907). Reverse transcription was performed

(7) Evolution of a core ribosomal innovation in octopusCurr BiolJuly 29, 2026Rishav Mitra, Richard Han, Trey J. Scott, Anik G. Grearson, Jessica A. Willi, Christina G. Liu, Hyeongju Kim, Michael C. Jewett, Nicholas W. Bellono, Amy S.Y. Leetyrosyl-tRNA synthetase (TyrRS), expressed in E. coli",This paper,N/A Murine RNase inhibitor,NEB,Cat#M0314S Micrococcal nuclease,NEB,N/A Q5 Hot Start DNA polymerase,NEB,Cat#M0491S T7 RNA polymerase (in-house

(8) Genome-wide chromatin recording resolves dynamic cell state changesbioRxivJuly 19, 2026Yodai Takei, Jordan A. Lay, James M. Linton, Duncan M. Chadly, Yoshiki Ochiai, Ron Hadas, Andrew A. Perez, Mario R. Blanco, Paola Laurino, Mitchell Guttman, et al.reaction mixtures containing 1× CutSmart buffer with 20 nM DNA or 50 nM RNA with 1 unit RNase Inhibitor (M0314S, NEB), 100 nM methyltransferase and 20 μM SAM. The methylation reaction in the 8 μL reaction was quenched

(9) Robust regulatory interplay of enhancers, facilitators, and promoters in a native chromatin contextCellJuly 17, 2026Zhou Zhou, Yang Cheng, Jaret Lieberth, Junke Zhang, Yiyang Jin, Albert Li, Haiyuan Yu, Abdullah Ozer, John T. Lisinhibitor,MilliporeSigma,Cat#3335399001 NlaIII,NEB,Cat#R0125L DpnII,NEB,Cat#R0543L Expand™ Long Template PCR System,MilliporeSigma,Cat#11681834001 "RNase Inhibitor, Murine",NEB,Cat#M0314L NEBNext® High-Fidelity 2X PCR Master Mix,NEB,Cat#M0541S Mix & Go! E. coli Buffer Set,Zymo Research,Cat#T3002 Critical

(10) Functional estrogenic activity in rivers, water supply, and rainwateriScienceJuly 17, 2026Gihani Manodara, Ashley Gillon, Emma S. Sutherland, Kelsey L. Stevens, Caitlin M. Deans, Alexia Kauff, Alison K. Heatherprotein 90 (HSP90, Abcam ab 80033), 90 ng ER lysate in trehalose buffer, 20U RNaseI inhibitor (NEB M0314L), and 15U T7 RNA polymerase (Life Biosciences T7T-70000) and 1 μL of eluate or 17β-estradiol (E2, Merck

(11) OTTR-CLASH: improved biochemical and bioinformatic identification of Argonaute 2-mediated microRNA-target RNA interactionsbioRxivJuly 15, 2026Paul D. Kaufman, Haibo Liu, Kai Hu, Lucas Ferguson, Kathleen Collins, Lihua Julie Zhu, Thoru Pedersonper 1 ml lysate, (2 U/μl) (Thermo, AM2239)) and Murine RNase inhibitor (22 μl per ml lysate, (NEB, M0314S)) for 5 minutes at 37°C with shaking at 1000 rpm in an Eppendorf thermomixer. Digested lysates were

(12) Analysis of senescence in pituitary tumors from different lineages and the potential role of senolytic drugs as targeted therapiesFront Endocrinol (Lausanne)July 15, 2026Sergio Andonegui-Elguera, Maria J. Gonzalez-Serrano, Sophia Mercado-Medrez, Silvia Hinojosa-Alvarez, Florencia Martinez-Mendoza, Itzel Ramirez-Ramos, Leilani A. Reyna-Coahutle, Arzu Y. Sanchez-Carbajal, Stefany R. Hernandez-Bustos, Alejandro Alegria-Ortega, et al.subsequent procedures were performed on ice. Firstly, an RNAse inhibitor (NEB, Ipswich, MA, USA; cat# M0314L) was added to the homogenization buffer (0.32 M sucrose, 1mM EDTA, 10mM Tris-HCl pH 7.4, 5 mM CaCl2,

(13) Crowdsourced riboregulators reveal design principles for programmable RNA switchingbioRxivJuly 9, 2026James M. Robson, Gabrielle Moussas, Dayna Francis, Alexander A. Greenwere added to each 5 μL cell-free reaction condition with 0.08 μL RNase Inhibitor (New England Biolabs M0314S). Each riboregulator design was tested either with cognate target (ON state) or with non-cognate decoy

(14) Protocol for minimized-bias profiling of liver and visceral adipose tissue in mice using integrated single-nucleus RNA sequencingSTAR ProtocJuly 8, 2026Lei Li, Jonathan G. Pol, Christophe Desterke, Wanchao Hu, Nicolas Trainel, Morgane Benardeau, Manuela Lizarralde-Guerrero, Maria Chiara Maiuri, Guido Kroemer, Gabriel Perlemuter, et al.DAPI Staining Solution,MILTENYI BIOTEC,Cat#130-111-570 "RNase inhibitor, 40000 U/mL",New England Biolabs,Cat#M0314 BD Stain Buffer (FBS),BD Biosciences,Cat#554656 "Proteinase K, 800 U/mL",New England Biolabs,Cat#P8107S Vybrant® DyeCycle™ Green Stain

(15) G protein-coupled receptor SmGPCR9 interacts with neuropeptides and controls spermatogenesis in Schistosoma mansoniPLoS PathogJuly 7, 2026Saranya Geetha, Simone Haeberlein, Steffen Hahnel, Xuesong Li, Daniel J. Sprague, Yuri K. Peterson, Shafqat Shabir, Franco H. Falcone, Moritz Buenemann, Christoph G. Grevelding(10 mM ATP, CTP, GTP and 7 mM UTP, 3.5 mM DTG-11-UTP), 0.6 µL Murine RNase inhibitor (40 U/µL, NEB, M0314S), and nuclease-free water (NEB, T2006-1) to make up the final volume to 20 µL. The reaction mixture

(16) A self-replicating artificial module-genome that generates bacterial chromosome replication system in vitroNucleic Acids ResJuly 6, 2026Yuta Yamagishi, Yoshiki Sonoyama, Naoki Kawakami, Tomonori Hasebe, Masayuki Su'etsugu1000 nM. T7 RNA polymerase from GeneFrontier (7.5 nM; Figs 2–4) was used. RNase Inhibitor Murine (NEB, M0314S) was added at 0.8 U/µl, and molecular chaperones DnaK mix (GeneFrontier, PF003) at 0.5 × and GroE mix

(17) Four-dimensional molecular mapping from a spatial snapshot reveals the dynamics of hair follicle organogenesisCellJuly 1, 2026Soichiro Asami, Chenshuo Yin, Jean Fan, Luis A. Garza, Reza KalhorThermostable inorganic pyrophosphatase,New England Biolabs,#M0296L "RNase inhibitor, murine",New England Biolabs,#M0314L Acryloyl-X,Invitrogen,#A20770 Bind-silane,Millipore Sigma,#M6514-25ML Acrylamide,Bio-Rad,#1610140 Bis-acrylamide,Bio-Rad,#1610142 "N,N,N’,N’-tetramethylethylenediamine

(18) Splicing dependency between EIF4G2 introns is mediated by exon definition and relies on a downstream splicing eventJournal of Biological ChemistryJune 27, 2026Marie-Lee Pelletier, Joëlle Vincent, Téa Malo, Camille Séguin, Volodymyr Tsybulskyi, Egor Semenchenko, Ibrahim Soumana Soumana Adamou, Irmtraud M. Meyer, Karine Choquetmin, 5 μl of 5X Induro RT reaction buffer, 0.2 μl of murine RNase Inhibitor (40 U/μl, NEB cat. no. M0314), 1 μl of Induro Reverse Transcriptase (200 U/μl, NEB, cat. no. M0681) and 4.8 μl of nuclease-free water

(19) Acute viral encephalitis impacts dense-core amyloid plaque pathology and dysregulates myeloid responses to amyloid plaquesAlzheimers DementJune 26, 2026Dominic Ibarra Javonillo, Susana Furman, Lucas Le, Kellie Fernandez, Jazmyn Mulford, Vidushi Singla, Roshni Jha, Kate Inman Tsourmas, Nellie E. Kwang, Kim N. Green, et al.(New England Biolabs, M0277L), Random Hexamers (Invitrogen, N8080127), RNAse Inhibitor (New England Biolabs M0314L) and AMV Buffer (New England Biolabs B0277A). Primer sequences used were glyceraldehyde‐3‐phosphate

(20) PDGF signaling regulates the adipocyte-to-fibroblast transition in wound healingCell ReportsJune 23, 2026Longbiao Yao, Sunhye Jeong, Jacob Bass, Hae Ryong Kwon, Lorin E. Olson1% NP-40, 1 mM DTT, 100 μg/mL cycloheximide, 1 mg/mL sodium heparin, 600 U/mL RNase inhibitor (NEB, M0314), and 1x Complete EDTA-free protease inhibitor in DEPC-treated H2O) on ice. After centrifugation at

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