RNase Inhibitor, Human Placenta from New England Biolabs

Product Specs
ItemRNase Inhibitor, Human Placenta
CompanyNew England Biolabs
Price $89.00 Inquire
Catalog NumberM0307S
Quantity2000 units
Concentration40,000 U/mL
SourceRecombinant E. Coli
ApplicationsFunctional Genomics
Temperature-20 C

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New England Biolabs

240 County Road

Ipswich, Massachusetts 1938

United States

Phone: 800-632-5227
800-632-7799
978-921-1350

Company Profile

Website: http://www.neb.com

(1) Regulation of YAP activity by nuclear G-actin bindingNucleic Acids ResMarch 19, 2026Hong Wang, Irma M Jayawardana, Justus M Fleisch, Dennis Frank, Bing Zhao, Christos Kamaras, Peter Gebhardt, Julian Knerr, Svenja Ulferts, Shamphavi Sivabalasarma, et al.ProtoScript II Buffer, 2 µL 0.1M DTT (Roth, 6908.1), 0.2 µL RNase Inhibitor (40 U/μl) (New England Biolabs, M0307S) and 1 µL ProtoScript® II Reverse Transcriptase (New England Biolabs, M0368L). Quantitative PCR (qPCR)

(2) Evolution of neurohormone function revealed by actions of kisspeptin-type peptides in an echinodermBMC BiologyFebruary 18, 2026Tabinda Islam, Luis A. Yañez-Guerra, Dean C. Semmens, Riley T. Beskeen, Michaela Egertová, Maurice R. Elphick5-mM dithiothreitol (Promega, Cat. No. P1171), 1 U/μl placental ribonuclease inhibitor (NEB, Cat. No. M0307S), and 5 U/μl of SP6 RNA polymerase (NEB, Cat. No. M0251S) for the antisense probe or 5 U/μl of T7 RNA polymerase

(3) Enhancing heritable genome editing in soybean by optimizing promoter combinations for the LbCas12a systemBMC Plant BiologyFebruary 14, 2026Jay Lv, Lizhao Geng, Wan Shi, Chao Li, Songyuan Wang, Boqi Zhang, Kun Yu, Ruijie Cui, Yubo Liu, Feng Xiong, et al.assembled with 10 fmol crRNA in 1x NEBuffer 3 (NEB, B7003S) supplemented with 40 U RNase inhibitor (NEB, M0307L) at 25 °C for 30 min. Then, 0.1 pmol target DNA was added to the reaction mixture and the mixture was

(4) Multi‐Tissue Omics Analysis Uncovers Translational Regulation Underlying Complex Traits in PigsAdvanced ScienceFebruary 3, 2026Chao Wang, Yuanyuan Zhang, Choulin Chen, Xiaoxian Xu, Shenghua Qin, Junyan Qi, Yongzhou Bao, Huiming Li, Ruipu Chen, Weigang Zheng, et al.then clarified by centrifugation at 20 000 × g for 3 min at 4°C. For each sample, 10 µL RNase I (NEB, M0307) and 6 µL DNase I (NEB, M0303) were added and incubated for 45 min at room temperature. Nuclease digestion

(5) Inhibiting translation elongation by reducing eIF5A activity induces feedback inhibition of initiation, limiting tumour cell proliferationNat CommunDecember 13, 2025Aristeidis P. Sfakianos, Rebecca M. Raven, Tom Smith, Xiao-Ming Sun, Thomas E. Mulroney, Mariavittoria Pizzinga, Veronica Dezi, Angela Rubio Tenor, Mark Stoneley, Cameron H. Cole, et al.cOmplete mini EDTA-free protease inhibitor cocktail (Merck, 11697498001), and 200 U RNase inhibitor (NEB, M0307L). The lysates were incubated at 4 °C for 5 min and subsequently centrifuged at 17,000 × g for 5 min

(6) The Epstein-Barr virus EBNA1 protein binds to G-quadruplexes in its own mRNA hence controlling its expression and immune evasion of the virusNucleic Acids ResJuly 4, 2025Van-Trang Dinh, Nadège Loaëc, Alicia Quillévéré, Marc Keruzoré, Aline Peynet, Ronan Le Sénéchal, Marie-Paule Teulade-Fichou, Laurent Corcos, Rodrigo Prado Martins, Anton Granzhan, et al.extracts or 600 ng of recombinant EBNA1 or NCL protein were treated with 200 U/mL of RNase Inhibitor (NEB, M0307S) for 90 min at 4°C on a rotating wheel. These extracts were then incubated with the RNA oligonucleotides

(7) Restoring endogenous Dlg4/PSD95 expression by an artificial transcription factor ameliorates cognitive and motor learning deficits in the R6/2 mouse model of Huntington's diseaseClin EpigeneticsJune 12, 2025Germán Fernández, Kevin Leiva, Fernando J. Bustos, Brigitte van Zundertreverse transcriptase (NEB, Cat. No. M0253S), 0.5 µL RNase inhibitor (New England biolabs, Cat. No. M0307S), 0.5 µL dNTP mix, and 6.5 µL nuclease-free water. The reaction mixture was incubated at 42 °C for 59

(8) Comprehensive nucleoside analysis of archaeal RNA modification profiles reveals an m7G in the conserved P loop of 23S rRNACell ReportsApril 22, 2025Yueh-Lin Tsai, Eric J. Wolf, Kristin A. Fluke, Ryan T. Fuchs, Nan Dai, Sean R. Johnson, Zhiyi Sun, Liam Elkins, Brett W. Burkhart, Thomas J. Santangelo, et al.37°C for 1 h. The digestion was stopped by adding 10 μL of human placental RNase inhibitor (NEB, Cat #M0307S) to the reaction mixture and incubated at room temperature for 10 min. Selective enrichment of the probe-hybridized

(9) Formin 3 stabilizes the cytoskeleton of Drosophila tendon cells, thus enabling them to resist muscle tensile forcesJournal of Cell ScienceApril 1, 2025Helena Pissarek, Na Huang, Leanna H. Frasch, Hermann Aberle, Manfred FraschDIG RNA Labeling Mix (Roche, cat. no. 11277073910), 2 µl RNase Inhibitor (New England BioLabs, cat. no. M0307), 200 ng purified PCR product, 2 µl T7 RNA Polymerase (Roche, cat. no. 10881775001). After incubation

(10) A Csde1-Strap complex regulates plasma cell differentiation by coupling mRNA translation and decayNat CommunMarch 25, 2025Pengda Chen, Lianghua Lin, Xinyong Lin, Kunyu Liao, Jiali Qiang, Zhizhang Wang, Jianfeng Wu, Yang Li, Liang Yang, Nan Yao, et al.centrifuged at 20,000 × g for 10 min at 4 °C. Supernatant was collected. 10 µL RNase I (NEB, Ipswich, USA, M0307) and 6 µL DNase I (NEB, Ipswich, USA, M0303) were added to 400 µL of lysate, followed by incubation

(11) CD14 is a decision-maker between Fas-mediated death and inflammationCell reportsSeptember 24, 2024Magri Z, Jetton D, Muendlein HI, Connolly WM, Russell H, Smirnova I, Sharma S, Bunnell S, Poltorak A.transcriptase,New England Biolabs,Cat#M0253 "RNase Inhibitor, Human Placenta",New England Biolabs,Cat#M0307 Random Primers 9,New England Biolabs,Cat#S1254 Deoxynucleoside Triphosphate (dNTP mix),New England

(12) Y-switch: a spring-loaded synthetic gene switch for robust DNA/RNA signal amplification and detectionNucleic Acids ResearchSeptember 23, 2024Krishna Gupta, Elisha KriegBioanalyzer 2100 (Supplementary Figure S7B). The RNA product was supplemented with RNAse inhibitor (NEB, #M0307), aliquoted, and stored at -80°C. The RNA concentration was quantified using a SARS-CoV-2 triplex PCR

(13) Nanodynamo quantifies subcellular RNA dynamics revealing extensive coupling between steps of the RNA life cycleNature CommunicationsSeptember 4, 2024Lucia Coscujuela Tarrero, Valeria Famà, Giacomo D’Andrea, Simone Maestri, Anna de Polo, Stefano Biffo, Mattia Furlan, Mattia Pelizzolacentrifugated at 110 g for 5 min and washed with ice cold PBS containing RNAse inhibitor (New England Biolabs M0307L). The pellet was resuspended in a cytoplasmic lysis buffer for the subsequent fractionation, following

(14) Splicing factor hnRNPA1 regulates alternative splicing of LOXL2 to enhance the production of LOXL2Δ13Journal of Biological ChemistryJuly 1, 2024Deyuan Pan, Lin Long, Chengyu Li, Yingxin Zhou, Qing Liu, Ziting Zhao, Hui Zhao, Wan Lin, Zhenyuan Zheng, Liu Peng, et al.NP-40, and 1.0% vol/vol Triton X-100, and an appropriate amount of RNase inhibitor (New England Biolabs, M0307) and protease inhibitor (MedChemExpress, HY-K0010) were added. Anti-hnRNPA1 antibody or IgG (Cell Signaling Technology

(15) Progressive alterations in polysomal architecture and activation of ribosome stalling relief factors in a mouse model of Huntington's diseaseNeurobiology of diseaseJune 1, 2024Martin-Solana E, Diaz-Lopez I, Mohamedi Y, Ventoso I, Fernandez JJ, Fernandez-Fernandez MR.μg/ml cycloheximide [CHX], heparin 20 μg/ml, and 40 U/ml RNase inhibitor [New England Biolabs, Cat. no. M0307S]) using a potter homogenizer (10–12 strokes). After three passages through a 23G needle, the homogenates

(16) LncRNA-SERB promotes vasculogenic mimicry (VM) formation and tumor metastasis in renal cell carcinomaJournal of Biological ChemistryMay 1, 2024Shuai Tang, Fangmin Chen, Jianghui Zhang, Fan Chang, Zheng Lv, Kai Li, Song Li, Yixi Hu, Shuyuan Yehwashed with cold 1× PBS, and then lysed with 1 ml cell lysis buffer with 100 units RNase inhibitor (M0307S, NEB). The cell lysates were frozen at −80 °C for 30 min, thawed on ice, and centrifuged to collect

(17) Quantitative analysis of transcription start site selection in Saccharomyces cerevisiae reveals control by DNA sequence, RNA Polymerase II activity, and NTP levelsNature Structural & Molecular BiologyJanuary 4, 2024Yunye Zhu, Irina O. Vvedenskaya, Sing-Hoi Sze, Bryce E. Nickels, Craig D. KaplanT4 polynucleotide kinase (Thermo Scientific, EK0031). M-MuLV Reverse Transcriptase (NEB, M0253L), RNase inhibitor (NEB, M0307L), dNTPs (GE) and DTT were added to mix of RNA and labelled primer for reverse transcription. Before

(18) Alternative splicing of BCL-x is controlled by RBM25 binding to a G-quadruplex in BCL-x pre-mRNANucleic Acids ResearchNovember 10, 2023Ronan Le Sénéchal, Marc Keruzoré, Alicia Quillévéré, Nadège Loaëc, Van-Trang Dinh, Oksana Reznichenko, Pedro Guixens-Gallardo, Laurent Corcos, Marie-Paule Teulade-Fichou, Anton Granzhan, et al.of cell extracts or 200 ng of recombinant RBM25 were treated with 200 U/mL of RNase Inhibitor (NEB, M0307S) for 90 min at 4°C on a rotating wheel. These extracts were then incubated with the RNA oligonucleotides

(19) Selective Characterization of mRNA 5′ End-Capping by DNA Probe-Directed Enrichment with Site-Specific EndoribonucleasesACS Pharmacology & Translational ScienceNovember 10, 2023Eric J. Wolf, Nan Dai, Siu-Hong Chan, Ivan R. Corrêarpm. hRNase 4 reactions were terminated by adding 1 μL of human placental RNase inhibitor (NEB no. M0307S) and incubating for 10 min at room temperature. Selective purification of the mRNA 5′ ends was performed

(20) Enzymatic Synthesis of High‐Density RNA MicroarraysCurrent ProtocolsFebruary 16, 2023Erika Schaudy, Jory Lietard, Mark M. SomozaThermoFisher Scientific, cat. no. 707265ML)RNase inhibitor, human placenta (40 U/µl) (NEB, cat. no. M0307)NTP set (100 mM each) (ThermoFisher Scientific, cat. no. R0481) Skirted reagent tubes with screw cap,

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