TransferMan® 4r Micromanipulator from Eppendorf

Product Specs
ItemTransferMan® 4r Micromanipulator
CompanyEppendorf
Price Get Pricing
Catalog Number5193000020
QuantityEA
ApplicationsMicromanipulation of suspension cells,ES and iPS cell transfer,Nucleus transfer, Production of transgenic animals using pronuclear and cytoplasmic injection (e.g. TALEN), Selection of individual cells (e.g. biopsies), Positioning and selection of microparticles Microdissection of chromosomes, etc. and applications in animal reproductive medicine (e.g. mouse ICSI)
Speed0 – 10,000 µm/s
TypeMicromanipulator
Resolution<20 nm
Dimensions(W x D x H) 12.9 mm × 5.1 mm × 3.6 cm
Weight2.15 kg
Operating Range0°– 90°

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Local Office

Eppendorf

100 Crossing Boulevard

Framingham, MA 01702

United States

Phone: 1-800-645-3050

Company Profile

Website: www.eppendorf.com

International Office

Eppendorf

Barkhausenweg 1

Hamburg 22339

Germany

Phone: +49 (0)1803 255 911

Email: eppendorf@eppendorf.de

Company Profile

Website: http://www.eppendorf.com/

(1) Target cell cortical tension regulates macrophage trogocytosisNat Cell BiolDecember 12, 2025Caitlin E. Cornell, Aymeric Chorlay, Deepak Krishnamurthy, Nicholas R. Martin, Lucia Baldauf, Daniel A. Fletcherunwanted adhesion of GUVs and target cells to the pipette glass. The treated pipettes were inserted into a TransferMan 4r micromanipulator (Eppendorf) mounted on a confocal microscope (Eclipse Ti2) to facilitate the manipulation of target

(2) Improving STR typing for low template DNA by abasic-site-mediated semi-linear preamplificationSci RepOctober 13, 2025Qiqi Ji, Zhimin Li, Zhimin Wang, Huaguang Yu, Fan Yang, Jianhui Xiecaptured with a microcapillary tip attached to a CellTram microinjector (Eppendorf, Germany) and a TransferMan 4r micromanipulator (Eppendorf, Germany). Captured cells were transferred directly into sterile 200 µL PCR tubes containing

(3) Effects of the Ecdysone Receptor on the Regulation of Reproduction in Coccinella septempunctataInsectsJune 19, 2025Ying Cheng, Yuhang Zhou, Cao Liadults were injected with 1 μL EcR-dsRNA or GFP-dsRNA (sham-injected controls) using the Eppendorf Transferman 4R Micromanipulator (Eppendorf, Germany). The adult ladybugs were placed in 25 mL plastic bottles and exposed to CO2 for

(4) Urea‐Loaded PLGA Microspheres as Chemotaxis Stimulants for Helicobacter pyloriBiotechnology and BioengineeringFebruary 1, 2025Prasanth Shanmughan, Pravin Subrahmaniyan, Dhruv Bhatnagar, Srinithi Ranganathan, Pushkar P. Lelewith a 6-micron diameter micro-capillary (Eppendorf piezo prill Tip ICSI) controlled with an Eppendorf Transferman 4r Micromanipulator. We continued recording the poststimulus response and analyzed the videos with either standard cell-tracking

(5) The neuroepithelial origin of ovarian carcinomas explained through an epithelial-mesenchymal-ectodermal transition enhanced by cisplatinScientific ReportsNovember 26, 2024David Díaz-Carballo, Ayesha Safoor, Sahitya Saka, Adrien Noa-Bolaño, Flevy D’Souza, Jacqueline Klein, Ali H. Acikelli, Sascha Malak, Udo Rahner, Amin T. Turki, et al.replaced with fresh medium to remove floating particles or dead cells. For the single cell sorting, the TransferMan®4r Micromanipulator from Eppendorf was used. First, a cell of interest was isolated from adjacent cells, by physically removing

(6) Inhibition of Rice Stripe Virus Accumulation by Polyubiquitin-C in Laodelphax striatellusInsectsFebruary 22, 2024Bo-Xue Li, Yu-Hua Qi, Chuan-Xi Zhang, Jian-Ping Chen, Jun-Min Li, Gang LuThird-instar nymphs were microinjected with 25 nl of dsLsUBC or dsGFP into insect hemolymph using a TransferMan 4r micromanipulator (Eppendorf, Hamburg, Germany). Following microinjection, nymphs were transferred to healthy rice seedlings

(7) Ectopic expression of human TUBB8 leads to increased aneuploidy in mouse oocytesCell discoveryOctober 24, 2023Dong J, Jin L, Bao S, Chen B, Zeng Y, Luo Y, Du X, Sang Q, Wu T, Wang L.prophase. Microinjection was performed using a Leica Hoffman microscope (DMi8, Leica) equipped with a TransferMan 4r micromanipulator, InjectMan 4, and FemtoJet 4i (Eppendorf). About 0.1%–0.3% volumes of cRNA solution were microinjected

(8) A novel kleptoplastidic symbiosis revealed in the marine centrohelid Meringosphaera with evidence of genetic integrationCurrent BiologySeptember 1, 2023Megan E.S. Sørensen, Vasily V. Zlatogursky, Ioana Onuţ-Brännström, Anne Walraven, Rachel A. Foster, Fabien Burkiphase contrast. Single cells that appeared to contain green/yellow bodies were isolated using an Eppendorf TransferMan 4r micromanipulator and pulled glass pipettes. The cells were passed through droplets of minimal seawater to reduce contamination

(9) Previously uncharacterized rectangular bacterial structures in the dolphin mouthNature CommunicationsApril 13, 2023Natasha K. Dudek, Jesus G. Galaz-Montoya, Handuo Shi, Megan Mayer, Cristina Danita, Arianna I. Celis, Tobias Viehboeck, Gong-Her Wu, Barry Behr, Silvia Bulgheresi, et al.Hoffman modulation optics. An Eppendorf TransferMan micromanipulator (Eppendorf, Hamburg, Germany, Cat. #5193000020) with a SAS-10 microinjector was used to capture RBS-As with Polar Body Biopsy Micropipettes (30° angled,

(10) The JAK-STAT pathway promotes persistent viral infection by activating apoptosis in insect vectorsPLOS PathogensMarch 16, 2023Yan Zhang, Bo-Xue Li, Qian-Zhuo Mao, Ji-Chong Zhuo, Hai-Jian Huang, Jia-Bao Lu, Chuan-Xi Zhang, Jun-Min Li, Jian-Ping Chen, Gang Luinjected with 25 nl of dsRNA into hemolymph in the insect ventral thorax via a glass needle based on a TransferMan 4r micromanipulator (Eppendorf, Hamburg, Germany). Injection of virus crude extracts Approximately 10 adult viruliferous

(11) Multiplexed Transgenic Selection and Counterselection Strategies to Expedite Genetic Manipulation Workflows Using Drosophila melanogasterCurrent ProtocolsFebruary 9, 2023Koen J. T. Venken, Nick Matinyan, Yezabel Gonzalez, Herman A. DierickAxiovert 40C) GELoader tips (Eppendorf, cat. no. 022351656) Transferman 4r (Eppendorf, cat. no. 5193000020) FemtoJet 4x (Eppendorf, cat. no. 5253000025) Foot control pedal (Eppendorf, cat. no. 920005799)

(12) Self-spinning filaments for autonomously linked microfibersNature CommunicationsFebruary 4, 2023Dylan M. Barber, Todd Emrick, Gregory M. Grason, Alfred J. CrosbyMSPs. Glass capillary tubes were inserted into a Capillary Holder 4 (Eppendorf), which was mounted in a TransferMan 4r micromanipulator (Eppendorf) and connected to a syringe pump loaded with aqueous solution for flow experiments. Thus

(13) Beer fermentation performance and sugar uptake of Saccharomycopsis fibuligera–A novel option for low-alcohol beerFrontiers in MicrobiologyOctober 5, 2022Yvonne Methner, Frederico Magalhães, Luis Raihofer, Martin Zarnkow, Fritz Jacob, Mathias Hutzlerhydrolase that might be present. Micromanipulation and yeast propagation For micromanipulation, a TransferMan® 4r micromanipulator with DualSpeed™ Joystic and CellTram® 4r Air, a pneumatic manual microinjector, were used (Eppendorf

(14) High throughput, label-free isolation of circulating tumor cell clusters in meshed microwellsNature communicationsJune 13, 2022Boya M, Ozkaya-Ahmadov T, Swain BE, Chu CH, Asmare N, Civelekoglu O, Liu R, Lee D, Tobia S, Biliya S, et al.and transferred to the PCR tubes containing RLT (Qiagen) + BME (Sigma-Aldrich) buffer using Eppendorf TransferMan 4r micromanipulator. During micromanipulation, the dish was supplemented with 1× PBS to prevent microwells from drying,

(15) Nanokit coupled electrospray ionization mass spectrometry for analysis of angiotensin converting enzyme 2 activity in single living cellChinese Chemical LettersMay 16, 2022Xinqi Chang, Nina Wang, Depeng Jiang, Hong-Yuan Chen, Dechen Jiangof 0 Psig. The voltage applied at the voltage is 4000 V. The micro-manipulation is performed using a TransferMan®4r micromanipulator (Eppendorf, Germany) using a microscope model Olympus X73 (Olympus, Japan). Single-cell electrochemical

(16) Effects of heterologous genome microinjection on the enlargement of Enterococcus faecalis protoplastsCurrent Research in Microbial SciencesJanuary 5, 2022Sawako Takahashi, Hiromi NishidaFL N objective 40×, and a UPlanFL N objective 60× . In addition, the microscope was equipped with a TransferMan 4r micromanipulator set (Eppendorf, Germany) with a FemtoJet 4i microinjector (Eppendorf, Germany). 2.3 Preparation of

(17) Auxin-dependent control of cytoskeleton and cell shape regulates division orientation in the Arabidopsis embryoCurrent BiologyNovember 22, 2021Prasad Vaddepalli, Thijs de Zeeuw, Sören Strauss, Katharina Bürstenbinder, Che-Yang Liao, João Jacob Ramalho, Richard S. Smith, Dolf WeijersConfocor 1 inverted microscope (Carl Zeiss Microscopy GmbH, Jena, Germany) together with an Eppendorf Transferman 4r micromanipulator (Eppendorf AG) and VacuTip II microcapillaries (Eppendorf) were used to isolate about 40-50 washed embryos

(18) Species-dependent protoplast enlargement involves different types of vacuole generation in bacteriaScientific ReportsDecember 1, 2020Sawako Takahashi, Marin Mizuma, Satoshi Kami, Hiromi Nishidamicroinjected into the cytoplasm of the E. faecalis protoplasts and L. amnigena spheroplasts using an Eppendorf TransferMan 4r micromanipulator (Supplementary Fig. 8). First, we used the enlarged E. faecalis protoplasts incubated in DMB. The protoplasts

(19) Cell Sorting in Hydra vulgaris Arises from Differing Capacities for Epithelialization between Cell TypesCurrent BiologyOctober 1, 2020Taylor D. Skokan, Ronald D. Vale, Kara L. McKinleyinto 1-4-cell stage Hydra embryos of the AEP SS1 strain using a FemtoJet 4i microinjector (Eppendorf), TransferMan 4r micromanipulator (Eppendorf), and dissecting microscope. Method Details Dissociation and reaggregation Dissociation

(20) Generation of Nonhuman Primate Model of Cone Dysfunction through In Situ AAV-Mediated CNGB3 AblationMolecular Therapy - Methods & Clinical DevelopmentSeptember 11, 2020Qiang Lin, Ji-Neng Lv, Kun-Chao Wu, Chang-Jun Zhang, Qin Liu, Zi-Bing JinDsRed signal were captured as controls. The targeted single-cone photoreceptors were captured using a TransferMan 4r micromanipulator (Eppendorf, Hamburg, Germany) with a glass pipette. To prevent negative effects of the cell suspension

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5/30/2017TransferMan For Precise Micromanipulation Alexandra AmbricoThe goal of our research is to create a more efficient metastatic prostate cancer GEMM and we will be using both the femtojet and transferman to inject virus cells into our current mouse model and ... Read Review