BioFrac™ Fraction Collector from Bio-Rad

Product Specs
ItemBioFrac™ Fraction Collector
CompanyBio-Rad
Price Supplier Page View Company Product Page
Catalog Number7410002
DimensionsDimensions (W x D x H): 44.5 x 35.6 x 38.7 cm (17.5 x 14.0 x 15.2")
QuantityEA
VolumeVolume: 0.02–99,999 ml
Temperature4–40°C

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Bio-Rad

Bio-Rad Laboratories, Inc. Life Science Research Group 2000 Alfred Nobel Drive

Hercules, California 94547

United States

Phone: 800-424 6723
800-879 2289

Company Profile

Website: http://discover.bio-rad.com

(1) Discovery of Iron-Chelating Peptides from Lupinus mutabilis via Integrated Purification and In Silico ValidationFoodsApril 10, 2026Zayra Vila-Santillán, David Campos, Ana Aguilar-Galvez, Sebastien Carpentier, Thomás Valente de Oliveira, Romina Pedreschi, Rosana Chirinospurchased from Sigma-Aldrich (St. Louis, MO, USA). The column was connected to a BioLogic LP system and a BioFrac fraction collector (Bio-Rad). Prior to metal loading, the column was equilibrated with six bed volumes of Milli-Q water.

(2) A family portrait of lanmodulin selectivity for enhanced rare-earth separationsNature Chemical BiologyMarch 18, 2026Patrick Diep, Cody S. Madsen, Wonseok Choi, Ziye Dong, Christina S. Kang-Yun, Patricia F. V. Uychoco, Jeremy A. Seidel, Samuel A. Eaton, Yongqin Jiao, Joseph A. Cotruvo, et al.agarose columns, the bottom valve can be connected to the outlet port on a fraction collector (Bio-Rad, 7410002) with an ice bath/microplate adaptor holding the appropriate number of 96-deepwell blocks. Column experiments

(3) A Comparative Study on the Effect of Near-Infrared Fluorescent Dyes on the Pharmacokinetic Behavior of Nanobody-Based Tracers for In Vivo ImagingJournal of Medicinal ChemistryNovember 13, 2025Noemi B. Declerck, Sofie Declercq, Pieterjan Debie, Julie Du Du Ville, Łukasz Mateusiak, Jelena Saliën, Marcus C. M. Stroet, Michael P. Luciano, Dong-Hao Li, Martin J. Schnermann, et al.(350 μL) with a 280 nm absorption above 80 milli-absorbance units (mAU) were automatically collected (BioFrac Fraction Collector, Bio-Rad Laboratories, CA, USA). After purification, the Nb and fluorophore concentration of all collected

(4) Development of an FKBP12-recruiting Chemical-Induced Proximity DNA-Encoded Library and its application in discovery of an autophagy potentiatorCell Chemical BiologyMarch 20, 2025Zher Yin Tan, Joel K. A. Adade, Xiebin Gu, Cody J. S. Hecht, Michael Salcius, Bingqi Tong, Shuang Liu, Seungmin Hwang, Frédéric J. Zécri, Daniel B. Graham, et al.performed using a Masterflex L/S easy-load II (Cole Parmer, 77200-50) running at approx 1 mL/min and BioFrac™ fraction collector (Bio-Rad) with a fraction time window of 2 min, i.e., (approx 2 mL fractions). Total electrophoresis

(5) A highland-adaptation variant near MCUR1 reduces its transcription and attenuates erythrogenesis in TibetansCell GenomMarch 12, 2025Ping J, Liu X, Lu Y, Quan C, Fan P, Lu H, Li Q, Wang C, Zhang Z, Liu M, et al.centrifugation, gradients were fractionated and the optical density at 254 nm was continuously recorded using a BioFrac fraction collector (CA, USA), and chased with 60% (w/v) sucrose with bromophenol blue at 1 mL/min. Data were analyzed using

(6) Mining yeast diversity unveils novel targets for improved heterologous laccase production in Saccharomyces cerevisiaeMicrob Cell FactMarch 10, 2025Ryan Wei Kwan Wong, Marissa Foo, Jasmine R. S. Lay, Tiffany L. T. Wai, Jackson Moore, Fabien Dutreux, Cristen Molzahn, Corey Nislow, Vivien Measday, Joseph Schacherer, et al.described in Bulter et al. [14], skipping the additional Mono Q step. 1 mL fractions were collected with a BioFrac Fraction collector (Bio-Rad) and active fractions were pooled and concentrated to 300 µL with a 30 kDa cut-off centrifugal

(7) Reconstitution of the Melibiose Permease of Salmonella enterica serovar Typhimurium (MelB_St) into Lipid NanodiscsBIO-PROTOCOLAugust 5, 2024Parameswaran Hariharan, Lan Guanpresents the chromatogram of the MelBSt nanodiscs. The chromatogram peak fractions collected using the BioFrac fraction collector can be directly used for downstream applications such as biochemical studies [15,18], cryo-EM single-particle analysis

(8) Interaction of Acinetobacter sp. RIT 592 induces the production of broad-spectrum antibiotics in Exiguobacterium sp. RIT 594Frontiers in PharmacologyAugust 1, 2024Anutthaman Parthasarathy, Renata Rezende Miranda, T. J. Bedore, Lizabeth M. Watts, Pavan K. Mantravadi, Narayan H. Wong, Jonathan Chu, Joseph A. Adjei, Amisha P. Rana, Michael A. Savka, et al.FT fractions from SAX/SPE were performed on the NGC Quest 10 Chromatography System equipped with a BioFrac fraction collector (Bio-Rad, USA) and a reverse-phase Zorbax Eclipse XDB-C18 semi-preparative column (9.4 × 250 mm, 5 μm,

(9) Activation of nemo-like kinase in diamond blackfan anemia suppresses early erythropoiesis by preventing mitochondrial biogenesisJournal of Biological ChemistryAugust 1, 2024Mark C. Wilkes, Aya Shibuya, Y. Lucy Liu, Kailen Mark, Jaqueline Mercado, Mallika Saxena, Ryan S. Sathianathen, Hye Na Kim, Bertil Glader, Paraic Kenny, et al.Optima L-80 ultracentrifuge with no brake. Samples were analyzed on the Bio-Rad BioLogic LP system and BioFrac fraction collector, and chased with 60% (w/v) sucrose with bromophenol blue at 1 ml/min. Data were analyzed using the Bio-Rad

(10) Rational design of structure‐based vaccines targeting misfolded alpha‐synuclein conformers of Parkinson's disease and related disordersBioengineering & Translational MedicineJuly 1, 2024Jose Miguel Flores‐Fernandez, Verena Pesch, Aishwarya Sriraman, Enrique Chimal‐Juarez, Sara Amidian, Xiongyao Wang, Caleb Duckering, Andrew Fang, Sara Reithofer, Liang Ma, et al.and the fractions containing the recombinant vaccine candidates were automatically collected using BioFrac™ Fraction Collector (Bio‐Rad Laboratories, Hercules, CA) when the 280 nm absorbance was greater than 0.05. The purity and

(11) Offline Two-Dimensional Liquid Chromatography–Mass Spectrometry for Deep Annotation of the Fecal Metabolome Following Fecal Microbiota TransplantationJournal of Proteome ResearchJune 7, 2024Brady G. Anderson, Alexander Raskind, Rylan Hissong, Michael K. Dougherty, Sarah K. McGill, Ajay S. Gulati, Casey M. Theriot, Robert T. Kennedy, Charles R. Evansand a post-column tee was used to establish a 50:1 effluent split between a Bio-Rad (Hercules, CA) BioFrac fraction collector and an Agilent 6520 quadrupole time of flight mass (QTOF) spectrometer operated as described in the

(12) Probing altered receptor specificities of antigenically drifting human H3N2 viruses by chemoenzymatic synthesis, NMR, and modelingNature CommunicationsApril 6, 2024Luca Unione, Augustinus N. A. Ammerlaan, Gerlof P. Bosman, Elif Uslu, Ruonan Liang, Frederik Broszeit, Roosmarijn van der Woude, Yanyan Liu, Shengzhou Ma, Lin Liu, et al.exclusion Biogel (P2) from BioRad in Econo glass columns (0.7 × 30 cm/1.5 × 30 cm/1.5 × 50 cm) coupled to a BioFrac fraction collector (BioRad). Carbohydrate-containing fractions were detected by thin-layer chromatography and an appropriate

(13) Optimization of Hydrolysis Conditions, Isolation, and Identification of Biologically Active Peptides Derived from Acheta domesticus for Antioxidant and Collagenase InhibitionAntioxidants (Basel)March 18, 2024Kankanit Yeerong, Panuwan Chantawannakul, Songyot Anuchapreeda, Sutee Wangtueai, Wantida ChaiyanaBioLogic low-pressure chromatography system (Bio-Rad Laboratories, Hercules, CA, USA) connected to a Biofrac fraction collector. The elution was performed with DI water at a flow rate of 0.5 mL/min. All the collected fractions,

(14) A Novel 3D-Printed and Miniaturized Periodic Counter Current Chromatography System for Continuous Purification of Monoclonal AntibodiesMicromachines (Basel)March 13, 2024Carlotta Kortmann, Taieb Habib, Christopher Heuer, Dörte Solle, Janina BahnemannHellma GmbH & Co. KG, Mülheim, Germany), was also set in-line after each CU. A fraction collector (BioFrac™ Fraction Collector, BioRad, CA, USA) with a fraction size of 1 mL was then added to save selected fractions for further

(15) Investigating dynamics of lentiviral vector secretion from HEK293T producer cells using a fractionated perfusion systemBiotechnology JournalJanuary 1, 2024Lauren M. Timmins, Patrick Erickson, Biju Parekkadanare described in detail in our previous publications.[25–27] A BioFrac fraction collector (Bio-Rad #7410002) was used to investigate the secretion dynamics over time from HEK293T cells in different conditions.

(16) Immune Portrayal of a New Therapy Targeting Microbiota in an Animal Model of PsoriasisJournal of Personalized MedicineOctober 30, 2023Mihaela Surcel, Carolina Constantin, Adriana Narcisa Munteanu, Diana Antonia Costea, Gheorghița Isvoranu, Elena Codrici, Ionela Daniela Popescu, Cristiana Tănase, Alef Ibram, Monica Neagupeak was pooled by repeated injection with the corresponding test tube through the fraction collector (BioFrac Fraction Collector, Bio-Rad, Hercules, CA, USA). Additional technical details are to be found in the filled patent [26]. 2.2.

(17) An unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitoreLifeOctober 16, 2023Tim Aguirre, Gillian L Dornan, Sarah Hostachy, Martin Neuenschwander, Carola Seyffarth, Volker Haucke, Anja Schütz, Jens Peter von Kries, Dorothea FiedlerSpectrophotometer. All recombinant proteins were purified on a Bio-Rad NGC chromatography system with a BioFrac Fraction Collector. NMR spectra were recorded on a Bruker SUPERSHIELD 600 PLUS. Luminescence assays were read out with

(18) A cell culture system to model pharmacokinetics using adjustable-volume perfused mixing chambersToxicology in VitroSeptember 1, 2023Patrick Erickson, Gunjan Jetley, Param Amin, Aamena Mejevdiwala, Ashna Patel, Kelli Cheng, Biju Parekkadanwas collected in fractions using a modified fraction collector (BioFrac Fraction Collector, Bio-Rad 7410002) until all the dye exited the system, after which the dye concentration was measured in 100 ul samples

(19) Diversity-oriented synthesis encoded by deoxyoligonucleotidesNat CommunAugust 15, 2023Liam Hudson, Jeremy W. Mason, Matthias V. Westphal, Matthieu J. R. Richter, Jonathan R. Thielman, Bruce K. Hua, Christopher J. Gerry, Guoqin Xia, Heather L. Osswald, John M. Knapp, et al.performed using a Masterflex L/S easy-load II (Cole Parmer, 77200-50) running at approx 1 mL/min and BioFrac™ fraction collector (Bio-Rad) with a fraction time window of 2 min, i.e., (approx 2 mL fractions). Total electrophoresis

(20) Dynamics of Ex Vivo Mesenchymal Stromal Cell Potency under Continuous PerfusionInternational journal of molecular sciencesMay 31, 2023Doshi A, Erickson P, Teryek M, Parekkadan B.connected the outlet of each bioreactor to a fraction collector (BioFrac Fraction Collector, Bio-Rad 7410002, Hercules, CA, USA) outside the incubator with a custom modification allowing it to collect from multiple

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