DGKB, Active from AAA Biotech, LLC

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DGKB, Active

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Description

Recombinant full-length human DGKB was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. The DGKB gene accession number is NM_004080.
Diacylglycerol kinase beta (DAG kinase beta) is a member of class I diacylglycerol kinase family and is regulated by Ca+ (1). Via converting diacylglycerol into phosphatidic acid, diacylglycerol kinases decrease the diacylglycerol levels to regulate the activity of PKC, Rho and Ras families (2). DGK beta is localized in brain and is involved in emotion and long-term memory linked to cognitive function (3). Impaired levels of diacylglycerol by DGK beta limits the NADpHoxidase activation in phagosomes (4)