Mca-PLGL-Dpa-AR-NH2 Fluorogenic MMP Substrate ES001 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemMca-PLGL-Dpa-AR-NH2 Fluorogenic MMP Substrate
CompanyR&D Systems, a Bio-Techne Brand
Price $562.00Supplier Page View Company Product Page
Catalog NumberES001
Size1 mg
ApplicationsBioactivity, Binding Activity
Molecular Weight1093 Da
SpeciesMulti-Species
Molecule NameProtease Substrates
ImmunogenMca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2
StorageSamples are stable for up to twelve months from date of receipt at -20° C to -70° C. The substrate can be aliquoted and stored -20° C to -70° C in a manual defrost freezer for six months. Avoid repeated freeze-thaw cycles. Protect from exposure to direct light

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(41) ProMMP-2: TIMP-1 Complexes Identified in Plasma of Healthy IndividualsConnective Tissue ResearchJanuary 23, 2012Stanley Zucker, Cathleen E. Schmidt, Antoine Dufour, Robert C. Kaplan, Robert C. Kaplan, Weiping Jianghour. Proteolytic activity of MMP-2 was monitored by the cleavage of a fluorogenic peptide substrate, ES001 (R&D Systems). MMP-2 (10 µg/ml) was incubated with recombinant TIMP-1 (R&D Systems) at 10-fold molar

(42) The cystatin M/E-cathepsin L balance is essential for tissue homeostasis in epidermis, hair follicles, and corneaFASEB journal : official publication of the Federation of American Societies for Experimental BiologyOctober 1, 2010Zeeuwen PL, van Vlijmen-Willems IM, Cheng T, Rodijk-Olthuis D, Hitomi K, Hara-Nishimura I, John S, Smyth N, Reinheckel T, Hendriks WJ, et al.

(43) Pharmacological profiles of animal- and nonanimal-derived sulfated polysaccharides - comparison of unfractionated heparin, the semisynthetic glucan sulfate PS3, and the sulfated polysaccharide fraction isolated from Delesseria sanguineaGlycobiologyDecember 25, 2008Inken Groth, Niels Grunewald, Susanne AlbanMMP-1 (c = 0.5 μg/mL in Tris buffer). After incubation for 5 min at 37°C, 25 μL of substrate solution (ES001 = Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2, c = 20 μM in Tris buffer, R&D Systems) was added. After another

(44) IFN-gamma regulation of vacuolar pH, cathepsin D processing and autophagy in mammary epithelial cellsJournal of cellular biochemistrySeptember 1, 2008Khalkhali-Ellis Z, Abbott DE, Bailey CM, Goossens W, Margaryan NV, Gluck SL, Reuveni M, Hendrix MJ.

(45) Decreased pathology and prolonged survival of human DC-SIGN transgenic mice during mycobacterial infectionJournal of immunology (Baltimore, Md. : 1950)May 15, 2008Schaefer M, Reiling N, Fessler C, Stephani J, Taniuchi I, Hatam F, Yildirim AO, Fehrenbach H, Walter K, Ruland J, et al.

(46) Microparticles of human atherosclerotic plaques enhance the shedding of the tumor necrosis factor-alpha converting enzyme/ADAM17 substrates, tumor necrosis factor and tumor necrosis factor receptor-1The American journal of pathologyNovember 1, 2007Canault M, Leroyer AS, Peiretti F, Lesèche G, Tedgui A, Bonardo B, Alessi MC, Boulanger CM, Nalbone G.

(47) Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancerCancer cellJuly 1, 2006Zhou BB, Peyton M, He B, Liu C, Girard L, Caudler E, Lo Y, Baribaud F, Mikami I, Reguart N, et al.

(48) Resuscitation of Hypoxic Piglets with 100% O2 Increases Pulmonary Metalloproteinases and IL-8Pediatric ResearchSeptember 9, 2005Berit Holthe Munkeby, Wenche Bakken Børke, Kristin Bjørnland, Liv Ingunn B Sikkeland, Grethe Iren A Borge, Jon Lømo, Santiago Rivera, Michel Khrestchatisky, Bente Halvorsen, Ola Didrik Saugstadactivity. Total MMP activity in tissue extracts was measured using a fluorogenic peptide substrate (cat no. ES001; R&D Systems, Minneapolis, MN) according to the protocol recommended by the manufacturer. The substrate

(49) Expression of matrix metalloproteinases in patients with Wegener's granulomatosisAnnals of the Rheumatic DiseasesDecember 1, 2004V Bjerkeli, B Halvorsen, J K DamÃ¥s, I NordÃ¸y, A Yndestad, P Aukrust, S S FrÃ¸landsupernatants was measured by a fluorogenic peptide substrate (R&D systems, Minneapolis, MN; cat no: ES001) using the protocol recommended by the manufacturer. Briefly, the MMP substrate was diluted in TCN www.annrheumdis.com A Controls Remission 90 80 MMP/rpL-32

(50) Resuscitation with 100% O2 Increases Cerebral Injury in Hypoxemic PigletsPediatric ResearchNovember 1, 2004Berit H Munkeby, Wenche B Børke, Kristin Bjørnland, Liv I B Sikkeland, Grethe I A Borge, Bente Halvorsen, Ola D SaugstadTotal MMP activity in tissue extracts was measured using a fluorogenic peptide substrate (cat. no. ES001; R&D Systems) according to the protocol recommended by the manufacturer. The substrate can be cleaved

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Mca-PLGL-Dpa-AR-NH2 Fluorogenic MMP Substrate from R&D Systems, a Bio-Techne Brand

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R&D Systems, a Bio-Techne Brand

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Mca-PLGL-Dpa-AR-NH2 Fluorogenic MMP Substrate from R&D Systems, a Bio-Techne Brand

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