GM-CSF Protein 415-ML-010 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemGM-CSF Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $303.00Supplier Page View Company Product Page
Catalog Number415-ML-010
SpeciesMouse
Size10 ug (also 5 ug, 20 ug, 50 ug)
Molecule NameGM-CSF
FormatLyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein
Purity>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemE. coli-derived Recombinant Mouse GM-CSF Protein
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene Namecolony stimulating factor 2
NCBI Gene AliasesCSF, GMCSF
Molecular Weight14.3 kDa

Specifications/Features

Available conjugates: Sizes Available: 10 ug (also 5 ug, 20 ug, 50 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

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(2) Th17 effector cytokines induce shared and distinct microglial and endothelial cell responses in a mouse model for post-streptococcal encephalitisNature CommunicationsAugust 11, 2026Charlotte R. Wayne, Uğur Akcan, Travis E. Faust, Violeta Durán-Laforet, Danny Jamoul, Luca Bremner, Nicole Ampatey, Büşra T. Akcan, Sarah J. Ho, Bogoljub Ciric, et al.IFNγ (R&D Systems, 485-MI-100), mouse IL-17A (R&D Systems, 7956-ML-025), mouse GM-CSF (R&D Systems, 415-ML-010) or vehicle (PBS with Ca2+ and Mg2+) was applied to corresponding wells. Transendothelial electrical

(3) GM-CSF increases glucose uptake and mitochondrial activity and reduces reactive oxygen species levels in mouse cumulus-oocyte complexes during oocyte in vitro maturationJournal of Reproduction and DevelopmentAugust 1, 2026Anmol SAINI, Hannah E LYONS, Nicole O MCPHERSON, Mark B NOTTLE[15] containing 0 and 10 ng/ml of recombinant mouse GM-CSF (R&D Systems, Minneapolis, MN, USA; Cat# 415-ML-010). A dose of 10 ng/ml was chosen because we previously showed that it increases embryo development as

(4) Dual Role of LBH589 in Triple‐Negative Breast Cancer: Inhibition of Tumor Growth and Enhancement of Antitumor ImmunityCancer Rep (Hoboken)May 21, 2026Liang Anjing, Yuan Rong, Xiang Su, Cheng Liang, Hou Jue, Chen Zhu(1 × 106/well) were seeded into 24‐well plate with 1640 medium containing GM‐CSF 20 ng/mL (Cat. no. 415‐ML‐010, R&D Systems, USA) and IL‐4 20 ng/mL (Cat. no. P07750, Novo Protein, China), and the medium was changed

(5) IFNγ-dependent metabolic reprogramming restrains an immature, pro-metastatic lymphatic state in melanomaCancer cellApril 13, 2026Karakousi T, Cristaldi V, Lopes de Oliveira ML, Delclaux I, Besson NR, Geraldo LH, González-Robles TJ, McDonnough DR, Martinez-Krams D, da Silva G, et al.with glutamine, 2-mercaptoethanol (Sigma-Aldrich, M6250), 10% FBS and 20 ng/ml GM-CSF (R&D Systems, 415-ML-010). Half of the medium was removed on day 2 and replenished with warmed complete RPMI medium with 40 ng/ml

(6) Neogambogic acid promotes M-MDSC differentiation into M1 macrophages to inhibit peritoneal metastasis of colorectal cancerInternational immunopharmacologyMarch 15, 2026Liu J, Wu Z, Xun J, Jiang X, Liu B, Yang H, Han Y, Hu Z, Gao Q, Zhang A, et al.

(7) Th17 effector cytokines induce shared and distinct microglial and endothelial cell responses in post-streptococcal encephalitisbioRxivFebruary 7, 2026Charlotte R. Wayne, Ugur Akcan, Travis E. Faust, Violetta Duran-Laforet, Danny Jamoul, Luca Bremner, Nicole Ampatey, Büşra T. Akcan, Sarah J. Ho, Bogoljub Ciric, et al.IFNγ (R&D Systems, 485-MI-100), mouse IL-17A (R&D Systems, 7956-ML-025), mouse GM-CSF (R&D Systems, 415-ML-010) or vehicle (PBS with Ca2+ and Mg2+) was applied to corresponding wells. Transendothelial electrical

(8) Antigen cross-presentation potentiating cancer vaccine adjuvant for T cell expansion and synergy with anti-PD-1npj VaccinesJanuary 21, 2026Giang Chau Dang, Vandara Loeurng, Paopachapich Pa, Chheng Y Seng, Shee Eun Lee, Joon Haeng Rheein 10 ml of dendritic cell-medium (DC-medium) (completed RPMI supplemented with 3 ng/ml of mGM-CSF (415-ML-010, R&D system, USA) and titrated amounts of recombinant proteins). The cell suspension was then plated

(9) Allogeneic MHC-mismatched microglia-like cell replacement as a therapeutic approach for multiple sclerosisJournal of neuroinflammationJanuary 8, 2026Benito-Cuesta I, Min JH, Guo Y, Virgilio GA, Suerth V, Bencina S, Trigo-Alonso P, Zhu K, Kung SY, Pahlevan Kakhki M, et al.(R&D systems, 5195-ML-010) and 10ng/ml granulocyte-macrophage colony stimulating factor (GM-CSF) (R&D systems, 415-ML-010) to promote MLC differentiation. Cells were cultured at 37 °C and 5% CO2 in a T175-cell culture flask

(10) Antigen-specific B cell response regulation by IL-10-producing tolerogenic dendritic cellsScience advancesNovember 21, 2025Morali K, Steuten J, Russo F, Romana Santoni de Sio F, Menage C, Consoli V, Annoni A, Iaia S, van Ham SM, Ten Brinke A, et al.

(11) Identification of UVB-induced TREM-1–positive tolerogenic dendritic cells and TREM-1 signaling as a target in the prevention of UVB-induced immune suppression and skin carcinogenesisJournal of Investigative DermatologyNovember 8, 2025Carlos Alberto Mier-Aguilar, Mohammad Asif Sherwani, Yuko Tsuruta, Noha Abdelsamad, David K. Crossman, Sejong Bae, Andrzej T. Slominski, Craig A. Elmets, Nabiha Yusuf, Hui XuL-glut, supplemented with 10% FBS, 1% antibiotic-antimycotic, 20 ng/ml of GM-CSF (R&D Systems, cat: 415-ML-010), and 10 ng/ml of IL-4 (R&D Systems, cat: 404-ML-010) in non-Tissue culture treated plates. We added

(12) Early Locus Coeruleus noradrenergic axon loss drives olfactory dysfunction in Alzheimer's diseaseNature communicationsAugust 8, 2025Meyer C, Niedermeier T, Feyen PLC, Strübing FL, Rauchmann BS, Karali K, Gentz J, Tillmann YE, Landgraf NF, Rumpf SL, et al.

(13) Granulocyte-Macrophage Colony-Stimulating Factor Inhibition Ameliorates Innate Immune Cell Activation, Inflammation, and Salt-Sensitive HypertensionCellsJuly 24, 2025Smith HL, Goodlett BL, Peterson GC, Zamora EN, Gostomski AR, Mitchell BM.

(14) Aberrant engagement of P-selectin drives hematopoietic stem cell aging in miceNat AgingJune 1, 2025Yang D, Skinder N, Kao YR, Chen J, Thiruthuvanathan V, Flohr Svendsen A, Zhang C, Dethmers-Ausema B, Weersing E, Maryanovich M, et al.supplemented with 420 ng/mL SCF, 20 ng/mL IL-11, 1 ng/mL Flt-3 ligand and GM-CSF 34 ng/mL (R&D Systems, 415-ML-010). Colonies were scored at day 7 and 14. For differentiation assay, 200 LT-HSCs were cultured in StemSpan

(15) Regulatory T cells suppress GM-CSF-producing T helper cells via IL-2 modulation to restrain immunopathologyCell reportsMay 27, 2025Costa-Pereira S, Lanzinger M, Núñez N, Villar-Vesga J, Andreadou M, Prisco F, Häne P, Roussel E, Krishnarajah S, Chanel Lindemann R, et al.

(16) RSV-Induced Regulation of DC via H3K4 Demethylase KDM5bEuropean journal of immunologyMay 1, 2025Mire MM, Martinez LA, Cortes AM, Morris S, Rasky A, Ptaschinski C, Lukacs NW.

(17) Impact of Chitosan Nanoparticles-Coated Dendritic Cell-Based Vaccine as Cancer ImmunotherapyVaccinesApril 28, 2025Alrahimi JS, Alotaibi NS, Aldahlawi AM, Basingab FS, Zaher KA.

(18) Kinetically activating nanovaccine mimicking multidimensional immunomodulation of natural infection for broad protection against heterologous viruses in animal modelsNature communicationsMarch 25, 2025Lee SN, Kim YI, Kim J, Haluwana DK, Eun R, Park SH, Heo J, Gil J, Seong Y, Lee MH, et al.

(19) Nonenzymatic lysine D-lactylation induced by glyoxalase II substrate SLG dampens inflammatory immune responsesCell researchFebruary 1, 2025Zhao Q, Wang Q, Yao Q, Yang Z, Li W, Cheng X, Wen Y, Chen R, Xu J, Wang X, et al.

(20) Interferon-γ production in response to the cytotoxic T lymphocyte epitope within an antigen incorporated in simian virus 40 virus-like particlesHeliyonJanuary 30, 2025Watanabe T, Hayashi M, Arai M, Matsushita S, Handa H, Kawano M.

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10/11/2024Mouse GM-CSF Protein From R&D Systems Showed a Great Effect on Endothelial Cell Migration Raj KumarThe study aimed to test the effect of GM-CSF on endothelial cell migration. To this end, mouse endothelial cells were growth-arrested, treated with recombinant mouse GM-CSF protein, and subjected to a... Read Review

Recombinant Mouse GM-CSF Protein

GM-CSF Protein

GM-CSF Protein

GM-CSF Protein

GM-CSF Protein

GM-CSF Protein from R&D Systems, a Bio-Techne Brand

Description

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (413)

Reviews

GM-CSF Protein from R&D Systems, a Bio-Techne Brand

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