Recombinant Mouse GM-CSF Protein 415-ML-010 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Mouse GM-CSF Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $303.00Supplier Page View Company Product Page
Catalog Number415-ML-010
SpeciesMouse
Size10 ug (also 5 ug, 20 ug, 50 ug)
Molecule NameGM-CSF
FormatLyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein
Purity>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular Weight14.3 kDa
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemE. coli-derived Recombinant Mouse GM-CSF Protein
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene Namecolony stimulating factor 2 (granulocyte-macrophage)
NCBI Gene AliasesCSF, Csfgm, GMCSF, Gm-CSf, MGI-IGM

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Th17 effector cytokines induce shared and distinct microglial and endothelial cell responses in post-streptococcal encephalitisbioRxivFebruary 7, 2026Charlotte R. Wayne, Ugur Akcan, Travis E. Faust, Violetta Duran-Laforet, Danny Jamoul, Luca Bremner, Nicole Ampatey, Büşra T. Akcan, Sarah J. Ho, Bogoljub Ciric, et al.IFNγ (R&D Systems, 485-MI-100), mouse IL-17A (R&D Systems, 7956-ML-025), mouse GM-CSF (R&D Systems, 415-ML-010) or vehicle (PBS with Ca2+ and Mg2+) was applied to corresponding wells. Transendothelial electrical

(2) IFNγ-dependent metabolic reprogramming restrains an immature, pro-metastatic lymphatic state in melanomaCancer CellJanuary 22, 2026Triantafyllia Karakousi, Vanessa Cristaldi, Maria Luiza Lopes de Oliveira, Ines Delclaux, Naomi R. Besson, Luiz Henrique Geraldo, Tania J. González-Robles, Devyon R. McDonnough, Daniel Martinez-Krams, Gabrielle da Silva, et al.with glutamine, 2-mercaptoethanol (Sigma-Aldrich, M6250), 10% FBS and 20 ng/ml GM-CSF (R&D Systems, 415-ML-010). Half of the medium was removed on day 2 and replenished with warmed complete RPMI medium with 40 ng/ml

(3) Antigen cross-presentation potentiating cancer vaccine adjuvant for T cell expansion and synergy with anti-PD-1npj VaccinesJanuary 21, 2026Giang Chau Dang, Vandara Loeurng, Paopachapich Pa, Chheng Y Seng, Shee Eun Lee, Joon Haeng Rheein 10 ml of dendritic cell-medium (DC-medium) (completed RPMI supplemented with 3 ng/ml of mGM-CSF (415-ML-010, R&D system, USA) and titrated amounts of recombinant proteins). The cell suspension was then plated

(4) Allogeneic MHC-mismatched microglia-like cell replacement as a therapeutic approach for multiple sclerosisJournal of NeuroinflammationJanuary 8, 2026Irene Benito-Cuesta, Jin-Hong Min, Yuxi Guo, Giulia Adriana Virgilio, Valerie Suerth, Stefan Bencina, Paula Trigo-Alonso, Keying Zhu, Shin-Yu Kung, Majid Pahlevan Kakhki, et al.(R&D systems, 5195-ML-010) and 10ng/ml granulocyte-macrophage colony stimulating factor (GM-CSF) (R&D systems, 415-ML-010) to promote MLC differentiation. Cells were cultured at 37 °C and 5% CO2 in a T175-cell culture flask

(5) Identification of UVB-induced TREM-1–positive tolerogenic dendritic cells and TREM-1 signaling as a target in the prevention of UVB-induced immune suppression and skin carcinogenesisJournal of Investigative DermatologyNovember 8, 2025Carlos Alberto Mier-Aguilar, Mohammad Asif Sherwani, Yuko Tsuruta, Noha Abdelsamad, David K. Crossman, Sejong Bae, Andrzej T. Slominski, Craig A. Elmets, Nabiha Yusuf, Hui XuL-glut, supplemented with 10% FBS, 1% antibiotic-antimycotic, 20 ng/ml of GM-CSF (R&D Systems, cat: 415-ML-010), and 10 ng/ml of IL-4 (R&D Systems, cat: 404-ML-010) in non-Tissue culture treated plates. We added

(6) Early Locus Coeruleus noradrenergic axon loss drives olfactory dysfunction in Alzheimer's diseaseNature communicationsAugust 8, 2025Meyer C, Niedermeier T, Feyen PLC, Strübing FL, Rauchmann BS, Karali K, Gentz J, Tillmann YE, Landgraf NF, Rumpf SL, et al.

(7) Regulatory T cells suppress GM-CSF-producing T helper cells via IL-2 modulation to restrain immunopathologyCell reportsMay 27, 2025Costa-Pereira S, Lanzinger M, Núñez N, Villar-Vesga J, Andreadou M, Prisco F, Häne P, Roussel E, Krishnarajah S, Chanel Lindemann R, et al.

(8) RSV-Induced Regulation of DC via H3K4 Demethylase KDM5bEuropean journal of immunologyMay 1, 2025Mire MM, Martinez LA, Cortes AM, Morris S, Rasky A, Ptaschinski C, Lukacs NW.

(9) Kinetically activating nanovaccine mimicking multidimensional immunomodulation of natural infection for broad protection against heterologous viruses in animal modelsNature communicationsMarch 25, 2025Lee SN, Kim YI, Kim J, Haluwana DK, Eun R, Park SH, Heo J, Gil J, Seong Y, Lee MH, et al.

(10) Nonenzymatic lysine D-lactylation induced by glyoxalase II substrate SLG dampens inflammatory immune responsesCell researchFebruary 1, 2025Zhao Q, Wang Q, Yao Q, Yang Z, Li W, Cheng X, Wen Y, Chen R, Xu J, Wang X, et al.

(11) Interferon-γ production in response to the cytotoxic T lymphocyte epitope within an antigen incorporated in simian virus 40 virus-like particlesHeliyonJanuary 30, 2025Watanabe T, Hayashi M, Arai M, Matsushita S, Handa H, Kawano M.

(12) Calycosin suppresses the activating effect of granulocyte-macrophage-colony-stimulating factor-producing T helper cells on macrophages in experimental atherosclerosisFrontiers in pharmacologyJanuary 1, 2025Xiong X, Huang W, Yang X, Wang X, Wu B, Li D.

(13) Alveolar macrophages are early targets of mumps virusProceedings of the National Academy of Sciences of the United States of AmericaDecember 24, 2024Patel AR, Garg A, Rosberger HT, Kowdle S, Reis RA, Frere JJ, Januska MN, Dawodu G, Valencia E, Yang MC, et al.

(14) Addition of granulocyte macrophage colony stimulating factor (GM-CSF) during in vitro oocyte maturation improves embryo development in a mouse model of advanced maternal ageThe Journal of reproduction and developmentDecember 13, 2024Saini A, McPherson NO, Nottle MB.[13] containing 0 and 10 ng/ml of recombinant mouse GM-CSF (R&D Systems, Minneapolis, MN, USA; Cat# 415-ML-010). GM-CSF was reconstituted as per supplier instructions in PBS plus 0.1% BSA (10 µg/ml) and frozen down

(15) IFNγ-dependent metabolic reprogramming restrains an immature, pro-metastatic lymphatic state in melanomabioRxiv : the preprint server for biologyDecember 5, 2024Karakousi T, Cristaldi V, Lopes de Oliveira ML, Medeiros Geraldo LH, González-Robles TJ, da Silva G, Breazeale AP, Encarnacion-Rosado J, Pozniak J, Kimmelman AC, et al.

(16) Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy modelNeuronDecember 4, 2024Carling GK, Fan L, Foxe NR, Norman K, Wong MY, Zhu D, Corona C, Razzoli A, Yu F, Yarahmady A, et al.

(17) Neutrophil extracellular traps promote tumor chemoresistance to anthracyclinesbioRxiv : the preprint server for biologyNovember 11, 2024Lin C, Herlihy SE, Li M, Deng H, Kim R, Bernabei L, Rosenwasser M, Gabrilovich DI, Vogl DT, Nefedova Y.

(18) Carboxylesterase 1 directs the metabolic profile of dendritic cells to a reduced inflammatory phenotypeJournal of leukocyte biologyNovember 4, 2024Elfiky AMI, Canñizares JL, Li J, Li Yim AYF, Verhoeven AJ, Ghiboub M, de Jonge WJ.

(19) Prebiotics Mitigate the Detrimental Effects of High-Fat Diet on memory, anxiety and microglia functionality in Ageing MiceBrain, behavior, and immunityNovember 1, 2024Vijaya AK, Kuras S, Šimoliūnas E, Mingaila J, Makovskytė K, Buišas R, Daliri EB, Meškys R, Baltriukienė D, Burokas A.

(20) Knockdown of microglial iron import gene, Slc11a2, worsens cognitive function and alters microglial transcriptional landscape in a sex-specific manner in the APP/PS1 model of Alzheimer’s diseaseJournal of NeuroinflammationSeptember 27, 2024Katrina Volk Robertson, Alec S. Rodriguez, Jean-Philippe Cartailler, Shristi Shrestha, Michael W. Schleh, Kyle R. Schroeder, Arianna M. Valenti, Alec T. Kramer, Fiona E. Harrison, Alyssa H. Hastypoly-L-lysine-coated 48-well plates in pre-warmed sterile IMG media containing 5 ng/mL GM-CSF (R&D Systems, #415-ML-010). Media was changed the next day, and then every other day for 5 days before stimulation with Aβ as

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10/11/2024Mouse GM-CSF Protein From R&D Systems Showed a Great Effect on Endothelial Cell Migration Raj KumarThe study aimed to test the effect of GM-CSF on endothelial cell migration. To this end, mouse endothelial cells were growth-arrested, treated with recombinant mouse GM-CSF protein, and subjected to a... Read Review

Recombinant Mouse GM-CSF Protein

GM-CSF Protein

GM-CSF Protein

GM-CSF Protein

GM-CSF Protein

Recombinant Mouse GM-CSF Protein from R&D Systems, a Bio-Techne Brand

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R&D Systems, a Bio-Techne Brand

Citations (402)

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Recombinant Mouse GM-CSF Protein from R&D Systems, a Bio-Techne Brand

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