Topoisomerase I is a subfamily of topoisomerases that are involved in the topology of DNA, particularly during transcription and DNA replication. There are two main types of topoisomerase I: type IA and IB. Type IA can only relax negatively supercoiled DNA while type IB can introduce positive supercoils. Type IA enzymes can cleave a single strand of supercoiled DNA to form a 5'- phosphotyrosyl intermediate while IB enzymes form a 3'-phosphotyrosyl intermediate. Topoisomerase I enzymes can be used for relaxing positively and negatively supercoiled DNA in certain molecular biology experiments. Visit the supplier page for more enzyme information.
Your search returned 25 Topoisomerase I across 8 suppliers.
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Sponsored Products
MyBioSource.com
- Description: Recombinant TOP1 70kDa protein is an enzyme fragment having a molecular mass of 69,199 Dalton (pH 9.4). ...
- 0.02 mg
- Western Blot (WB), ELISA (EIA)
Abbexa Ltd
- Recombinant Topoisomerase I (TOP1) is a recombinant Human protein produced in E. coli using Prokaryotic expression
- 10 µg, 50 µg, 100 µg, 200 µg, 1 mg
- WB, SDS-PAGE
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Novus Biologicals, a Bio-Techne Brand
MyBioSource.com
- Description: DNA Topoisomerase-I Human Recombinant produced in SF9 is a glycosylated, polypeptide chain having a ...
- 0.02 mg
- Inquire
- This gene encodes a mitochondrial DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA ...
- 0.02 mg (E-Coli)
- Inquire
RayBiotech
- 20 ug, 1 mg
- Western blot with Scleroderma patient sera or monoclonal ...
New England Biolabs
- Recognizes non-perfectly matched DNA
- Isolated from a recombinant source
- Supplied with 10X Reaction Buffer
Description:
...
500 unitsDNA Manipulation
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- Recognizes non-perfectly matched DNA
- Isolated from a recombinant source
- Supplied with 10X Reaction Buffer
Description:
...
100 unitsDNA Manipulation
Read More
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