The Biocompare Inhibitor Search Tool lets researchers browse thousands of compounds by searching by inhibitor name or by its target enzyme. Simply search by “Keywords” if you know the name of the inhibitor, or search by “Inhibitor Target” to enter the name of your protein of interest. Additionally, you may check the appropriate boxes to narrow down your search.
Caspase-5 is an inflammatory cysteine protease that plays a role in the innate immune system. Along with caspase-1 it is also sometimes involved in inflammasome activation. Caspase-5 inhibitors are sought for their ability to halt inflammatory processes. Most currently available caspase-5 inhibitors are peptide-based, though some small-molecule inhibitors can be purchased. Recent efforts have attempted to expand the number of caspase-5 specific inhibitors so as to further study their role separate from that of caspsase-1.
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