LRRC8C ELISA kits are immunoassay tools for the measurement of the protein leucine rich repeat containing 8 VRAC subunit C, which is encoded by the LRRC8C gene in humans. Functionally, this protein is reported to be a non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The canonical protein structure is reported to have an amino acid length of 803 residues, a mass of 92.5 kDa, and is a member of the LRRC8 protein family. It is known to be localized in the ER and cell membrane and is reported be expressed at highest levels in skeletal muscle, and at moderate levels in heart, lung and peripheral blood leukocytes. The protein has been noted to be post-translationally glycosylated. Other alias names for this target include factor for adipocyte differentiation 158, hypothetical protein AD158, leucine rich repeat containing 8 family member C, and volume-regulated anion channel subunit LRRC8C.
The detection range for different LRRC8C ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.