GREM1 ELISA kits are immunoassay tools for the measurement of the protein gremlin 1, DAN family BMP antagonist, which is encoded by the GREM1 gene in humans. Functionally, this protein is a reported cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. The canonical protein structure is reported to have an amino acid length of 184 residues, a mass of 20.7 kDa, and is a member of the DAN protein family. It is known to be secreted and is reported to be highly expressed in small intestine, fetal brain and colon. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally glycosylated. The GREM1 gene has been associated with the disease, Polyposis syndrome. Other alias names for this target include CKTSF1B1, CRAC1, CRCS4, DAND2, DRM, DUP15q, GREMLIN, and C15DUPq.
There are GREM1 ELISA kits that can detect a target at concentrations as low as 7.81 pg/mL and as high as 400 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.