The following Purine Nucleoside Phosphorylase ELISA kits are useful research tools for the measurement of purine nucleoside phosphorylase in biological samples. In humans this protein is encoded by the PNP gene. This protein is known to catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. The canonical protein structure is reported to have an amino acid length of 289 residues, a mass of 32.1 kDa, and is a member of the PNP/MTAP phosphorylase protein family. Its subcellular location is known to be in the cytoplasm. In addition, it is reported to be expressed in red blood cells; overexpressed in red blood cells (cytoplasm) of patients with hereditary non-spherocytic hemolytic anemia of unknown etiology. The gene encoding this protein has been associated with the disease, Purine nucleoside phosphorylase deficiency. This protein may also be known as PRO1837, PUNP, HEL-S-156an, epididymis secretory sperm binding protein Li 156an, inosine phosphorylase, and NP.
The detection range for different purine nucleoside phosphorylase ELISA kits can vary, with some assays measuring target concentrations as low as 3 ng/L and as high as 10 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.