WDR45 ELISA kits are immunoassay tools for the measurement of the protein WD repeat domain 45, which is encoded by the WDR45 gene in humans. Functionally, this protein is a known component of the autophagy machinery that controls the major intracellular degradation process by which cytoplasmic materials are packaged into autophagosomes and delivered to lysosomes for degradation. The canonical protein structure is reported to have an amino acid length of 360 residues, a mass of 39.9 kDa, and is a member of the WD repeat PROPPIN protein family. It is known to be localized in the cytoplasm and is widely expressed across many tissue types. As many as 3 protein isoforms have been reported. The WDR45 gene has been associated with the disease, Neurodegeneration with brain iron accumulation. Other alias names for this target include NBIA4, NBIA5, WDRX1, WIPI-4, WIPI4, and JM5.
There are WDR45 ELISA kits that can detect a target at concentrations as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.