CD74 ELISA kits are immunoassay tools for the measurement of the protein CD74 molecule, which is encoded by the CD74 gene in humans. Functionally, this protein is known to play an important role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. The canonical protein structure is reported to have an amino acid sequence of 296 residues and a mass of 33.5 kDa. It is known to be localized in the ER, golgi, lysosomes, cell membrane, and is secreted and is notably expressed in urine. The protein has been noted to be post-translationally O-glycosylated. The CD74 gene has been associated with the disease, . Other alias names for this target include DHLAG, HLADG, II, Ia-GAMMA, p33, and CLIP.
There are CD74 ELISA kits that can detect a target at concentrations as low as 30 pg/mL and as high as 200 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.