DDOST ELISA kits are immunoassay tools for the measurement of the protein dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit, which is encoded by the DDOST gene in humans. Functionally, this protein is a known subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. The canonical protein structure is reported to have an amino acid length of 456 residues, a mass of 50.8 kDa, and is a member of the DDOST 48 kDa subunit protein family. It is known to be localized in the ER. As many as 3 protein isoforms have been reported. The DDOST gene has been associated with the disease, Congenital disorder of glycosylation. Other alias names for this target include CDG1R, GATD6, OKSWcl45, OST, OST48, and AGER1.
Some DDOST ELISA kits can detect targets at levels as low as 0.15 ng/mL and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.