CCNF ELISA kits are immunoassay tools for the measurement of the protein cyclin F, which is encoded by the CCNF gene in humans. Functionally, this protein is reported to be a substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. The canonical protein structure is reported to have an amino acid length of 786 residues, a mass of 87.6 kDa, and is a member of the Cyclin protein family. It is known to be localized in the nucleus and cytoplasm and is found to be widely expressed, with expression detected in the heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. The protein has been noted to be post-translationally ubiquitinated and phosphorylated. The CCNF gene has been associated with the disease, Frontotemporal dementia and/or amyotrophic lateral sclerosis. Other alias names for this target include FBXO1, FTDALS5, F-box only protein 1, G2/mitotic-specific cyclin-F, and FBX1. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.