Ready-to-use ELISA kits are available for the detection of Grem, an alias of the protein, gremlin 1, DAN family BMP antagonist. The official gene symbol is GREM1. The protein, with a mass of 20.7 kDa and length of 184 residues, is reported to be secreted. It is a member of the DAN family and may be known by other names, including: gremlin 1 cysteine knot superfamily homolog, down-regulated in Mos-transformed cells protein, colorectal adenoma and carcinoma 1, cell proliferation-inducing gene 2 protein, DAN domain family member 2, and gremlin-1, and increased in high glucose-2.