The following cleavage and polyadenylation specific factor 3 ELISA kits are useful research tools for the measurement of cleavage and polyadenylation specific factor 3 in biological samples. In humans this protein is encoded by the CPSF3 gene. This protein is a known component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. The canonical protein structure is reported to have an amino acid length of 684 residues, a mass of 77.5 kDa, and is a member of the RNA-metabolizing metallo-beta-lactamase-like protein family. Its subcellular location is known to be in the nucleus. In certain instances, it is also post-translationally sumoylated. The gene encoding this protein has been associated with the disease, Neurodevelopmental disorder with microcephaly, hypotonia, nystagmus, and seizures. This protein may also be known as CPSF73, NEDMHS, NEDMHSN, cleavage and polyadenylation specificity factor subunit 3, cleavage and polyadenylation specific factor 3, 73kDa, and CPSF-73.
Some cleavage and polyadenylation specific factor 3 ELISA kits can detect targets at levels as low as 0.156 ng/mL and as high as 10 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.