ARHGEF11 ELISA kits are immunoassay tools for the measurement of the protein Rho guanine nucleotide exchange factor 11, which is encoded by the ARHGEF11 gene in humans. Functionally, this protein is believed to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). The canonical protein structure is reported to have an amino acid sequence of 1522 residues and a mass of 167.7 kDa. It is known to be localized in the cytoplasm and is ubiquitously expressed across many tissue types. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally ubiquitinated and phosphorylated. Other alias names for this target include PDZ-RHOGEF, Rho guanine exchange factor (GEF) 11, Rho guanine nucleotide exchange factor (GEF) 11, RhoA-specific guanine nucleotide exchange factor, and GTRAP48.
The detection range for different ARHGEF11 ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.