WEE1 ELISA kits are immunoassay tools for the measurement of the protein WEE1 G2 checkpoint kinase, which is encoded by the WEE1 gene in humans. Functionally, this protein is known to act as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onset of mitosis by mediating phosphorylation of CDK1 on 'Tyr-15'. The canonical protein structure is reported to have an amino acid length of 646 residues, a mass of 71.6 kDa, and is a member of the Ser/Thr protein kinase protein family. It is known to be localized in the nucleus. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally ubiquitinated and phosphorylated. Other alias names for this target include WEE1hu, wee1-like protein kinase, WEE1 homolog, WEE1+ homolog, protein kinase, wee1A kinase, and WEE1A.
Some WEE1 ELISA kits can detect targets at levels as low as 0.156 ng/mL and as high as 40 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.