The PGD2 synthase ELISA kits listed below utilize specific antibodies for the plate-based assay of PGD2 synthase in various samples. PGD2 synthase is another term for the PTGDS gene, which encodes the protein, prostaglandin D2 synthase in humans. The target protein is known to catalyze the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Structurally, the PTGDS protein is described to be 190 amino acid residues in length and 21 kilodaltons in mass. Its subcellular localization is in the nucleus, ER, golgi, cytoplasm, and is secreted. In terms of tissue specificity, it is notably expressed in the brain and CNS, where it is expressed in tissues of the blood-brain barrier and secreted into the cerebro-spinal fluid. This protein is known to be O-glycosylated and N-glycosylated. Other names for this target antigen include L-PGDS, L-PGDS, and LPGDS.