The following Plakophilin 2 ELISA kits are useful research tools for the measurement of plakophilin 2 in biological samples. In humans this protein is encoded by the PKP2 gene. This protein is reported to regulate focal adhesion turnover resulting in changes in focal adhesion size, cell adhesion and cell spreading, potentially via transcriptional modulation of beta-integrins. The canonical protein structure is reported to have an amino acid length of 881 residues, a mass of 97.4 kDa, and is a member of the Beta-catenin protein family. Its subcellular location is known to be in the nucleus and cytoplasm. In addition, it is notably expressed in heart right ventricle. As many as 2 protein isoforms have been reported. The gene encoding this protein has been associated with the disease, Arrhythmogenic right ventricular dysplasia. This protein may also be known as ARVD9.
The detection range for different Plakophilin 2 ELISA kits can vary, with some assays measuring target concentrations as low as 10 ng/L and as high as 50 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.