MTRR ELISA kits are immunoassay tools for the measurement of the protein 5-methyltetrahydrofolate-homocysteine methyltransferase reductase, which is encoded by the MTRR gene in humans. Functionally, this protein is known to be a key enzyme in methionine and folate homeostasis responsible for the reactivation of methionine synthase (MTR/MS) activity by catalyzing the reductive methylation of MTR-bound cob(II)alamin. The canonical protein structure is reported to have an amino acid sequence of 698 residues and a mass of 77.7 kDa. It is known to be localized in the cytoplasm and is reported to be found in all tissues tested, particularly abundant in skeletal muscle. As many as 2 protein isoforms have been reported. The MTRR gene has been associated with the disease, Homocystinuria-megaloblastic anemia. Other alias names for this target include cblE, methionine synthase reductase, [methionine synthase]-cobalamin methyltransferase (cob(II)alamin reducing), aqCbl reductase, aquacobalamin reductase, and MSR.
There are Mtrr ELISA kits that can detect a target at concentrations as low as 78 pg/mL and as high as 5000 pg/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.