PBX1 ELISA kits are immunoassay tools for the measurement of the protein PBX homeobox 1, which is encoded by the PBX1 gene in humans. Functionally, this protein is known to be a transcription factor which binds the DNA sequence 5'-TGATTGAT-3' as part of a heterodimer with HOX proteins such as HOXA1, HOXA5, HOXB7 and HOXB8. The canonical protein structure is reported to have an amino acid length of 430 residues, a mass of 46.6 kDa, and is a member of the TALE/PBX homeobox protein family. It is known to be localized in the nucleus and is reported to be expressed in the kidney. As many as 3 protein isoforms have been reported. The PBX1 gene has been associated with the disease, Congenital anomalies of kidney and urinary tract syndrome with or without hearing loss. Other alias names for this target include pre-B-cell leukemia transcription factor 1, homeobox protein PBX1, homeobox protein PRL, pre-B-cell leukemia homeobox 1, and CAKUHED.
Some PBX1 ELISA kits can detect targets at levels as low as 78 pg/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.