DTL ELISA kits are immunoassay tools for the measurement of the protein denticleless E3 ubiquitin protein ligase homolog, which is encoded by the DTL gene in humans. Functionally, this protein is reported to be a substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The canonical protein structure is reported to have an amino acid length of 730 residues, a mass of 79.5 kDa, and is a member of the WD repeat cdt2 protein family. It is known to be localized in the membrane, nucleus, and cytoplasm and is reported to be expressed in placenta and testis, very low expression seen in skeletal muscle. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally ubiquitinated and phosphorylated. Other alias names for this target include DCAF2, L2DTL, RAMP, denticleless protein homolog, DDB1- and CUL4-associated factor 2, and CDT2.
There are DTL ELISA kits that can detect a target at concentrations as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.