NEU3 ELISA kits are immunoassay tools for the measurement of the protein neuraminidase 3, which is encoded by the NEU3 gene in humans. Functionally, this protein is a reported exo-alpha-sialidase that catalyzes the hydrolytic cleavage of the terminal sialic acid (N-acetylneuraminic acid, Neu5Ac) of a glycan moiety in the catabolism of glycolipids, glycoproteins and oligosacharides. The canonical protein structure is reported to have an amino acid length of 428 residues, a mass of 48.3 kDa, and is a member of the Glycosyl hydrolase 33 protein family. It is known to be localized in the lysosomes and cell membrane and is reported to be highly expressed in skeletal muscle, testis, adrenal gland and thymus, followed by pancreas, liver, heart and thymus. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally palmitoylated. Other alias names for this target include sialidase-3, N-acetyl-alpha-neuraminidase 3, ganglioside sialidase, ganglioside sialidasedis, membrane sialidase, and SIAL3.
Some NEU3 ELISA kits can detect targets at levels as low as 30 ng/L and as high as 15 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.