NRL ELISA kits are immunoassay tools for the measurement of the protein neural retina leucine zipper, which is encoded by the NRL gene in humans. Functionally, this protein is known to act as a transcriptional activator which regulates the expression of several rod-specific genes, including RHO and PDE6B. The canonical protein structure is reported to have an amino acid length of 237 residues, a mass of 25.9 kDa, and is a member of the BZIP protein family. It is known to be localized in the nucleus and cytoplasm and is reported to be expressed in the brain and the retina. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally sumoylated and phosphorylated. The NRL gene has been associated with the disease, Retinitis pigmentosa. Other alias names for this target include NRL-MAF, RP27, neural retina-specific leucine zipper protein, neural retinal-specific leucine zipper, and D14S46E.
The detection range for different NRL ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.