These DAP12 ELISA kits are immunodetection tools for measuring the levels of DAP12 in biological samples. DAP12 is an alias of the human TYROBP gene, which encodes the protein, transmembrane immune signaling adaptor TYROBP. Notably, DAP12 is known to play a role in cytoskeleton organization and the apoptotic pathway, among other functions. The TYROBP protein is 113 amino acid residues in length and 12.2 kilodaltons in mass. However, as many as 3 protein isoforms have been identified. It is localized to the cell membrane of the cell. In terms of tissue specificity, it is reported to be expressed at low levels in the early development of the hematopoietic system and in the promonocytic stage and at high levels in mature monocytes. This protein is known to be phosphorylated. Other names for this target antigen include KARAP.
The detection range for different DAP12 ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 20 ng/mL. Click on the following ELISA kits for more detailed information, including target reactivity and assay sensitivity.