PLEKHG3 ELISA kits are immunoassay tools for the measurement of the protein pleckstrin homology and RhoGEF domain containing G3, which is encoded by the PLEKHG3 gene in humans. Functionally, this protein is reported to play a role in in controlling cell polarity and cell motility by selectively binding newly polymerized actin and activating RAC1 and CDC42 to enhance local actin polymerization. The canonical protein structure is reported to have an amino acid sequence of 1219 residues and a mass of 134.4 kDa. It is known to be localized in the cytoplasm. As many as 3 protein isoforms have been reported. Other alias names for this target include KIAA0599, pleckstrin homology domain-containing family G member 3, PH domain-containing family G member 3, pleckstrin homology domain containing, family G (with RhoGef domain) member 3, and ARHGEF43.
The detection range for different PLEKHG3 ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.