KMT2E ELISA kits are immunoassay tools for the measurement of the protein lysine methyltransferase 2E (inactive), which is encoded by the KMT2E gene in humans. Functionally, this protein is reported to associate with chromatin regions downstream of transcriptional start sites of active genes and thus regulates gene transcription. The canonical protein structure is reported to have an amino acid length of 1858 residues, a mass of 205 kDa, and is a member of the Histone-lysine methyltransferase protein family. It is known to be localized in the nucleus, chromosomes, and cytoplasm and is found to be widely expressed in both adult and fetal tissues. As many as 8 protein isoforms have been reported. The protein has been noted to be post-translationally O-glycosylated and ubiquitinated. The KMT2E gene has been associated with the disease, O'Donnell-Luria-Rodan syndrome. Other alias names for this target include histone-lysine N-methyltransferase 2E, histone-lysine N-methyltransferase MLL5, inactive lysine N-methyltransferase 2E, and inactive histone-lysine N-methyltransferase 2E.
The detection range for different KMT2E ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.