PTTG1 ELISA kits are immunoassay tools for the measurement of the protein PTTG1 regulator of sister chromatid separation, securin, which is encoded by the PTTG1 gene in humans. Functionally, this protein is reported to be a regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. The canonical protein structure is reported to have an amino acid length of 202 residues, a mass of 22 kDa, and is a member of the Securin protein family. It is known to be localized in the nucleus and cytoplasm and is reported to be expressed at low level in most tissues, except in adult testis, where it is highly expressed. The protein has been noted to be post-translationally ubiquitinated and phosphorylated. Other alias names for this target include ECRAR, HPTTG, PTTG, TUTR1, securin, and EAP1.
Some PTTG1 ELISA kits can detect targets at levels as low as 20 ng/L and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.