The following Interferon Regulatory Factor 5 ELISA kits are useful research tools for the measurement of interferon regulatory factor 5 in biological samples. In humans this protein is encoded by the IRF5 gene. This protein is reported to be a transcription factor that plays a critical role in innate immunity by activating expression of type I interferon (IFN) IFNA and INFB and inflammatory cytokines downstream of endolysosomal toll-like receptors TLR7, TLR8 and TLR9. The canonical protein structure is reported to have an amino acid length of 498 residues, a mass of 56 kDa, and is a member of the IRF protein family. Its subcellular location is known to be in the nucleus and cytoplasm. As many as 6 protein isoforms have been reported. In certain instances, it is also post-translationally ubiquitinated and phosphorylated. The gene encoding this protein has been associated with the disease, Inflammatory bowel disease. This protein may also be known as SLEB10.
Some Interferon Regulatory Factor 5 ELISA kits can detect targets at levels as low as 3 ng/L and as high as 10 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.