Fig 1: ROC analysis of IFN-γ and IRF5. (A) ROC analysis revealed that a threshold value of 45.2 pg/mg protein for IFN-γ had a sensitivity of 100% and a specificity of 100% in determination of missed abortion (AUC, 1.0; P<0.001; LB, 1.0; and UB, 1.0). (B) A threshold value of 1.7 ng/mg protein for IRF5 had a sensitivity of 84.6% and a specificity of 90.9% in determination of missed abortion (AUC, 0.909; P=0.001; LB, 0.787; and UB, 1.0). ROC, receiver operating characteristic; IFN-γ, interferon-γ; IRF5, interferon regulatory factor 5; AUC, area under curve; LB, lower bound; UB, upper bound.
Fig 2: Protein and gene expression levels of IRF5 and IFN-? in missed abortion and voluntary abortion groups. Boxplots showing the comparisons of the mean (A) IRF5 and (B) IFN-? protein levels and (C) IRF5 and (D) IFN-? gene expression levels in the missed abortion and voluntary abortion groups. IRF5, interferon regulatory factor 5; IFN-?, interferon-?; GAPDH, glyceraldehyde-3-phosphate dehydrogenase.
Supplier Page from Wuhan Fine Biotech Co., Ltd. for Human IRF5(Interferon Regulatory Factor 5) ELISA Kit