GRIA4 ELISA kits are immunoassay tools for the measurement of the protein glutamate ionotropic receptor AMPA type subunit 4, which is encoded by the GRIA4 gene in humans. Functionally, this protein is a known receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. The canonical protein structure is reported to have an amino acid length of 902 residues, a mass of 100.9 kDa, and is a member of the Glutamate-gated ion channel (TC 1.A.10.1) protein family. It is known to be localized in the cell membrane. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally glycosylated, palmitoylated and phosphorylated. The GRIA4 gene has been associated with the disease, Neurodevelopmental disorder with or without seizures and gait abnormalities. Other alias names for this target include GLUR4C, GLURD, GluA4, GluA4-ATD, NEDSGA, glutamate receptor 4, AMPA-selective glutamate receptor 4, and GLUR4.
The detection range for different GRIA4 ELISA kits can vary, with some assays measuring target concentrations as low as 0.15 ng/mL and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.