The following sphingosine kinase 1 ELISA kits are useful research tools for the measurement of sphingosine kinase 1 in biological samples. In humans this protein is encoded by the SPHK1 gene. This protein is known to catalyze the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. The canonical protein structure is reported to have an amino acid sequence of 384 residues and a mass of 42.5 kDa. Its subcellular location is known to be in the cell membrane, nucleus, and cytoplasm. In addition, it is reported to be widely expressed with highest levels in adult liver, kidney, heart and skeletal muscle. As many as 3 protein isoforms have been reported. This protein may also be known as SK 1, SPK 1, acetyltransferase SPHK1, and SPHK.
The detection range for different sphingosine kinase 1 ELISA kits can vary, with some assays measuring target concentrations as low as 15.6 pg/mL and as high as 40 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.