FGFR3 ELISA kits are immunoassay tools for the measurement of the protein fibroblast growth factor receptor 3, which is encoded by the FGFR3 gene in humans. Functionally, this protein is reported to be a tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. The canonical protein structure is reported to have an amino acid length of 806 residues, a mass of 87.7 kDa, and is a member of the Tyr protein kinase protein family. It is known to be localized in the cytoplasmic vesicles, ER, and cell membrane and is reported to be expressed in the brain, kidney and testis. As many as 4 protein isoforms have been reported. The protein has been noted to be post-translationally N-glycosylated, ubiquitinated and phosphorylated. The FGFR3 gene has been associated with the disease, Achondroplasia. Other alias names for this target include CD333, CEK2, HSFGFR3EX, JTK4, fibroblast growth factor receptor 3-S, and ACH.
There are FGFR3 ELISA kits that can detect a target at concentrations as low as 30 ng/L and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.