The following ectonucleotide pyrophosphatase/phosphodiesterase 1 ELISA kits are useful research tools for the measurement of ectonucleotide pyrophosphatase/phosphodiesterase 1 in biological samples. In humans this protein is encoded by the ENPP1 gene. This protein is reported to be a nucleotide pyrophosphatase that generates diphosphate (PPi) and functions in bone mineralization and soft tissue calcification by regulating pyrophosphate levels (By similarity). The canonical protein structure is reported to have an amino acid length of 925 residues, a mass of 104.9 kDa, and is a member of the Nucleotide pyrophosphatase/phosphodiesterase protein family. Its subcellular location is known to be in the cell membrane. In addition, it is reported to be expressed in plasma cells and also in a number of non-lymphoid tissues, including the distal convoluted tubule of the kidney, chondrocytes and epididymis. In certain instances, it is also post-translationally N-glycosylated, cleaved and phosphorylated. The gene encoding this protein has been associated with the disease, Ossification of the posterior longitudinal ligament of the spine. This protein may also be known as COLED, M6S1, NPP1, NPPS, PC-1, PCA1, PDNP1, and ARHR2.
There are ectonucleotide pyrophosphatase/phosphodiesterase 1 ELISA kits that can detect a target at concentrations as low as 31.2 pg/mL and as high as 40 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.